ArticleMolecules (Basel, Switzerland)2015
Multi-Optimization of Ultrasonic-Assisted Enzymatic Extraction of Atratylodes macrocephala Polysaccharides and Antioxidants Using Response Surface Methodology and Desirability Function Approach.
Article in Molecules (Basel, Switzerland), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed, 34 citations in OpenAlex.
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- Optimization of trypsin extraction technology of Allium cepa L. polysaccharide by response surface methodology and the antitumor effects through immunomodulation.Bioengineered · 2021Article
- Production, purification, characterization, and biological properties of Rhodosporidium paludigenum polysaccharide.PloS one · 2021Article
- Ultrasonic-assisted enzymatic extraction ofRSC advances · 2020Article
- Microwave-Assisted Green Synthesis and Antioxidant Activity of Selenium Nanoparticles UsingMolecules (Basel, Switzerland) · 2019Article
- Optimization of Ultrasonic-Assisted Extraction and Purification of Zeaxanthin and Lutein in Corn Gluten Meal.Molecules (Basel, Switzerland) · 2019Article
- Optimization of the extraction, preliminary characterization, and anti-inflammatory activity of crude polysaccharides from the stems ofRSC advances · 2019Article
- Purification, Characterization, and Antioxidant Activity of Polysaccharides Isolated from Cortex Periplocae.Molecules (Basel, Switzerland) · 2017Article
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8 authors at 2 institutions in 1 country.
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Abstract
Rhizoma Atractylodes macrocephala polysaccharides (RAMP) have been reported to have a variety of important biological activities. In this study, an ultrasonic-assisted enzymatic extraction (UAEE) was employed to obtain the highest extraction yield and strongest antioxidant activity of RAMP and optimized by a multi-response optimization process. A three-level four-factor Box-Behnken design (BBD) was performed as response surface methodology (RSM) with desirability function (DF) to attain the optimal extraction parameters. The DPPH scavenging percentage was used to represent the antioxidant ability of RAMP. The maximum D value (0.328), along with the maximum yield (59.92%) and DPPH scavenging percentage (13.28%) were achieved at 90.54 min, 57.99 °C, 1.95% cellulase and 225.29 W. These values were further validated and found to be in good agreement with the predicted values. Compared to the other extraction methods, both the yield and scavenging percentage of RAMP obtained by UAEE was favorable and the method appeared to be time-saving and of high efficiency. These results demostrated that UAEE is an appropriate and effective extraction technique. Moreover, RSM with DF approach has been proved to be adequate for the design and optimization of the extraction parameters for RAMP. This work has a wide range of implications for the design and operation of polysaccharide extraction processes.
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