Evidence map›Paper›PMID 26690399›Full record

SynthesisMolecules (Basel, Switzerland)2015

Impact of Natural Juice Consumption on Plasma Antioxidant Status: A Systematic Review and Meta-Analysis.

Fernanda S Tonin, Laiza M Steimbach, Astrid Wiens, Cássio M Perlin, Roberto Pontarolo

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Molecules (Basel, Switzerland), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 3 pooled it
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 3 syntheses or guidelines pooled it, 33 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Fernanda S ToninDepartment of Pharmacy, Pharmaceutical Sciences Postgraduate Program, Universidade Federal do Paraná, Av. Prof. Lothario Meissner 632, 80210-170 Curitiba, Brazil. fer_stumpf_tonin@hotmail.com.
Laiza M SteimbachDepartment of Pharmacy, Pharmaceutical Sciences Postgraduate Program, Universidade Federal do Paraná, Av. Prof. Lothario Meissner 632, 80210-170 Curitiba, Brazil. laizasteimbach@gmail.com.
Astrid WiensDepartment of Pharmacy, Pharmaceutical Sciences Postgraduate Program, Universidade Federal do Paraná, Av. Prof. Lothario Meissner 632, 80210-170 Curitiba, Brazil. astridwiens@hotmail.com.
Cássio M PerlinDepartment of Pharmacy, Postgraduate Program in Pharmaceutical Care, Universidade Federal do Rio Grande do Sul, Av. Paulo Gama 110, 90040-060 Porto Alegre, Brazil. mperlin.cassio@gmail.com.
Roberto PontaroloDepartment of Pharmacy, Pharmaceutical Sciences Postgraduate Program, Universidade Federal do Paraná, Av. Prof. Lothario Meissner 632, 80210-170 Curitiba, Brazil. pontarolo@ufpr.br.
Universidade Federal do Paraná · BRUniversidade Federal do Rio Grande do Sul · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOxidative stress may lead to overproduction of reactive species and a decrease in antioxidant defenses, resulting in chronic diseases such as diabetes and cancer. The consumption of natural compounds with an antioxidant profile may be a preventive alternative. Therefore, we aimed to obtain evidence regarding the potential antioxidant activity of juices in human plasma.

methodsA systematic review and meta-analysis was performed, which included randomized controlled trials that compared the use of fruit or vegetable juices vs. placebo or other beverages. An electronic search was conducted in PubMed, Scopus, International Pharmaceutical Abstracts, and SciELO. The outcome measures extracted were related to antioxidant status, e.g., vitamin C, superoxide dismutase (SOD), and catalase (CAT) levels and reduction in malondialdehyde (MDA) and antioxidant capacity measured as TEAC.

resultsTwenty-eight trials were identified (n = 1089), of which 16 were used for meta-analysis. No significant differences were observed between juices and placebo with regard to TEAC, SOD, and CAT. However, juices were superior to control in enhancing vitamin C and reducing MDA.

conclusionsNatural juices are possible candidates for the management of oxidative stress. The effects of juices should be further investigated by conducting larger and well-defined trials of longer duration.

Indexed as

BeveragesFruitAntioxidantsAscorbic AcidCatalaseEatingGlutathione PeroxidaseHumansMalondialdehydeOxidative StressRandomized Controlled Trials as TopicSuperoxide DismutaseAntioxidantsAscorbic AcidCatalaseGlutathione PeroxidaseMalondialdehydeSuperoxide Dismutaseantioxidant capacityhealth benefitsjuicesystematic review

Identifiers

PMID26690399
PMCPMC6331866
OpenAlexW2195404438

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.