Evidence map›Paper›PMID 26690165›Full record

ArticleSensors (Basel, Switzerland)2015

Evaluation of Chemical Interactions between Small Molecules in the Gas Phase Using Chemical Force Microscopy.

Jieun Lee, Soomi Ju, In Tae Kim, Sun-Hwa Jung, Sun-Joon Min, Chulki Kim, Sang Jun Sim, Sang Kyung Kim

Abstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jieun LeeCenter for Biomicrosystems, Korea Institute of Science and Technology (KIST), Hwarangno 14-gil 5, Seongbuk-gu, Seoul 136-791, Korea. simsj@korea.ac.kr.
Soomi JuCenter for Biomicrosystems, Korea Institute of Science and Technology (KIST), Hwarangno 14-gil 5, Seongbuk-gu, Seoul 136-791, Korea. ssumi0115@gmail.com.
In Tae KimCenter for Biomicrosystems, Korea Institute of Science and Technology (KIST), Hwarangno 14-gil 5, Seongbuk-gu, Seoul 136-791, Korea. fresh1606@naver.com.
Sun-Hwa JungCenter for Neuro-Medicine, Brain Science Institute, Korea Institute of Science and Technology(KIST), Hwarangno 14-gil 5, Seongbuk-gu, Seoul 136-791, Korea. shjung8748@gmail.com.
Sun-Joon MinDepartment of Applied Chemistry, Hanyang University, Sangnok-gu, Ansan, Gyeonggi-do 15588, Korea. sjmin@hanyang.ac.kr.
Chulki KimCenter for Sensor System Research, Korea Institute of Science and Technology (KIST), Hwarangno 14-gil 5, Seongbuk-gu, Seoul 136-791, Korea. chulki.kim@kist.re.kr.
Sang Jun SimDepartment of Chemical and Biological Engineering, Korea University, 5-ga Annam-dong, Seongbuk-gu, Seoul 136-713, Korea. simsj@korea.ac.kr.
Sang Kyung KimCenter for Biomicrosystems, Korea Institute of Science and Technology (KIST), Hwarangno 14-gil 5, Seongbuk-gu, Seoul 136-791, Korea. sangk@kist.re.kr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chemical force microscopy analyzes the interactions between various chemical/biochemical moieties in situ. In this work we examined force-distance curves and lateral force to measure the interaction between modified AFM tips and differently functionalized molecular monolayers. Especially for the measurements in gas phase, we investigated the effect of humidity on the analysis of force-distance curves and the images in lateral force mode. Flat chemical patterns composed of different functional groups were made through micro-contact printing and lateral force mode provided more resolved analysis of the chemical patterns. From the images of 1-octadecanethiol/11-mercapto-1-undecanoic acid patterns, the amine group functionalized tip brought out higher contrast of the patterns than an intact silicon nitride tip owing to the additional chemical interaction between carboxyl and amine groups. For more complex chemical interactions, relative chemical affinities toward specific peptides were assessed on the pattern of 1-octadecanethiol/phenyl-terminated alkanethiol. The lateral image of chemical force microscopy reflected specific preference of a peptide to phenyl group as well as the hydrophobic interaction.

Indexed as

BenzeneFatty AcidsGasesMicroscopy, Atomic ForcePeptidesSulfhydryl Compounds11-mercaptoundecanoic acidBenzeneFatty AcidsGasesn-octadecyl mercaptanPeptidesSulfhydryl Compoundsbenzene specific peptidechemical force microscopylateral force imagemicro-contact printing

Identifiers

PMID26690165
PMCPMC4721743

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.