ArticleAmerican journal of preventive medicine2016
Associations of Relative Handgrip Strength and Cardiovascular Disease Biomarkers in U.S. Adults, 2011-2012.
Article in American journal of preventive medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 170 papers, 2 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
170 citing papers in PubMed, 2 syntheses or guidelines pooled it, 304 citations in OpenAlex.
- Association of Handgrip Strength with Quality of Life in Breast Cancer Survivors: A Systematic Review and Meta-Analysis.Asian Pacific journal of cancer prevention : APJCP · 2022Pooled it
- The effect of additional protein on lean body mass preservation in post-bariatric surgery patients: a systematic review.Nutrition journal · 2021Pooled it
- Impact of low-intensity resistance and whole-body vibration training on aortic hemodynamics and vascular function in postmenopausal women.Hypertension research : official journal of the Japanese Society of Hypertension · 2019Trial
- The influence of resting blood pressure on muscle strength in healthy adults.Blood pressure monitoring · 2018Trial
- Associations of Fitness, Physical Activity, Strength, and Genetic Risk With Cardiovascular Disease: Longitudinal Analyses in the UK Biobank Study.Circulation · 2018Trial
- Aging-, obesity-, and diabetes-related sarcopenia: Pathogenesis and interventions.Chinese medical journal · 2026Review
- Association between handgrip strength and symptoms of anxiety and depression among university students: A cross-sectional study.Physiological reports · 2026Article
- Article
- Cross-cohort insights into the association of handgrip strength transitions and burdens with cardiovascular disease risk.SSM - population health · 2026Article
- Computed tomography-derived muscle quality and density and the risk of postoperative decline in exercise capacity in adults who received cardiac surgery: A retrospective cohort study.JPEN. Journal of parenteral and enteral nutrition · 2026Article
- Article
- Association between grip strength and hypertensive disorders of pregnancy: Prospective analyses in the Tongji-Huaxi-Shuangliu Birth Cohort.Chinese medical journal · 2026Article
- Socioeconomic Disparities in Cardiovascular Health: A Cross-Sectional Analysis Unpacking the Sequential Mediation Roles of Protein Intake and Handgrip Strength.Healthcare (Basel, Switzerland) · 2026Article
- Relationship between triglyceride-glucose index and muscle strength in middle-aged and older Chinese adults without chronic diseases: a nationwide longitudinal cohort study.Scientific reports · 2026Article
- Exercise reveals precocious-subclinical cardiovascular and muscular dysfunction in transfusion dependent beta-thalassemia (TDT) patients without cardiac iron overload.Journal of translational medicine · 2026Article
- Age moderates the association between handgrip strength and large artery stiffness in women.Journal of applied physiology (Bethesda, Md. : 1985) · 2026Article
- Vitamin D deficiency modifies the association between ambient PMNutrition research and practice · 2026Article
- Relative handgrip strength mediates the association between metabolic syndrome and health-related quality of life among Korean adult women.BMC research notes · 2026Article
- Association between relative muscle strength and circadian syndrome among middle-aged and older Chinese adults.Scientific reports · 2026Article
- Association between relative handgrip strength and glycemic control among male automobile manufacturing workers using vibration tools in South Korea.Annals of occupational and environmental medicine · 2026Article
110 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
introductionAlthough decline in muscle mass and quality and resulting declines in muscle strength are associated with aging, more research is needed in general populations to assess the utility of handgrip strength as an indicator of muscle strength and cardiovascular disease risk.
methodsData from 4,221 participants aged ≥20 years in the 2011-2012 cycle of National Health and Nutrition Examination Survey were analyzed during 2014-2015. Standing isometric relative handgrip strength (calculated as maximal absolute handgrip strength from both hands divided by BMI) was used to predict cardiovascular biomarkers, including blood pressure (measured systolic and diastolic blood pressure); serum lipids (total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, and triglycerides); and plasma insulin and glucose.
resultsResults from regression analyses showed that higher relative grip strength was significantly associated with lower systolic blood pressure, triglycerides, and plasma insulin and glucose, and higher high-density lipoprotein cholesterol in male and female participants (p<0.05 for all). Secondary descriptive analyses found that absolute handgrip strength increased significantly with increasing weight status, but relative handgrip strength decreased significantly with increasing weight status.
conclusionsResults suggest that increased relative handgrip strength may be associated with a better profile of cardiovascular health biomarkers among U.S. adults. Relative grip strength, which both adjusts for the confounding of mass and assesses concomitant health risks of increased body size and low muscle strength, may be a useful public health measure of muscle strength.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.