ArticleBMC cancer2015
The preoperative SUVmax for (18)F-FDG uptake predicts survival in patients with colorectal cancer.
Article in BMC cancer, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed.
- Prognostic significance of bone marrow and spleenScientific reports · 2021Trial
- Uncertainty-aware deep learning for classifying colonic fdg-pet uptake using radiomic features.Radiological physics and technology · 2026Article
- Texture analysis of [European journal of nuclear medicine and molecular imaging · 2026Observational
- Article
- Predictive Value of Preoperative Maximum Standardized Uptake Value (SUVmax) in Patients with Advanced Gastric Cancer.Biomedicines · 2025Article
- AAbdominal radiology (New York) · 2025Article
- PreoperativeCancers · 2024Article
- Preoperative metabolic parameters ofQuantitative imaging in medicine and surgery · 2024Article
- A fingerprint of 2-[iScience · 2023Article
- Predictive value ofJournal of cancer research and clinical oncology · 2023Article
- Contribution of Metabolic Parameters and Pericolic Fat Stranding on Preoperative 18F-FDG PET/CT in Predicting Post-operative Histopathology and Outcome in Colorectal Cancer.Nuclear medicine and molecular imaging · 2023Article
- Rectal MRI Interpretation After Neoadjuvant Therapy.Journal of magnetic resonance imaging : JMRI · 2023Review
- Efficacy of PET/CT in diagnosis of regional lymph node metastases in patients with colorectal cancer: retrospective cohort study.BJS open · 2022Article
- Article
- Prognostic Value of Intratumor Metabolic Heterogeneity Parameters onContrast media & molecular imaging · 2022Article
- Predictive value ofF1000Research · 2022Review
- FDG-PET/CT in colorectal cancer: potential for vascular-metabolic imaging to provide markers of prognosis.European journal of nuclear medicine and molecular imaging · 2021Observational
- Metabolic Phenotypes, Dependencies, and Adaptation in Lung Cancer.Cold Spring Harbor perspectives in medicine · 2021Review
- Radical lymphadenectomy of a para-aorta lymph node metastasis in colorectal cancer prolongs relapse-free survival.International journal of colorectal disease · 2021Article
- Prognostic value of metabolic parameters onScientific reports · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe study was to investigate whether (18)F-fluorodeoxyglucose ((18)F-FDG) uptake, analyzed by positron emission tomography (PET), can be used preoperatively to predict survival in Chinese patients with colorectal carcinoma.
methodsA prospectively maintained colorectal cancer database was retrospectively reviewed between June 2009 and December 2011. All included patients had been newly diagnosed with colorectal cancer (of various stages) and evaluated by (18)F-FDG-PET/computed tomography (CT) within the 2 weeks preceding surgery. Univariate and multivariate analyses were used to determine whether the maximal standardized uptake value (SUVmax) and various clinicopathological and immunohistochemical factors were correlated with survival. Receiver operating characteristics (ROC) curve and Kaplan-Meier survival curve analyses were used to explore whether SUVmax could predict survival in these patients.
resultsA total of 107 patients were enrolled in the study (mean age, 59.26 ± 12.66 years; 66.35% males), with 77 surviving to the end of follow-up (average 60 months). Univariate analysis indicated that tumor size, TNM stage, nodal metastasis, the ratio of metastasized nodes to retrieved nodes, cyclin D1 immunostaining and SUVmax correlated with survival (P < 0.05). Multivariate analysis showed that only TNM stage and SUVmax were associated with survival (P < 0.05). ROC curve analysis determined the optimal SUVmax cutoff for predicting survival to be 11.85 (sensitivity, 73.3%; specificity, 75.3%). Survival was significantly longer in patients with preoperative SUVmax ≤ 11.85 (P < 0.001, log-rank test).
conclusionsSUVmax, measured by (18)F-FDG-PET/CT, provides a useful preoperative prognostic factor for patients with colorectal cancer.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.