Evidence map›Paper›PMID 26689781›Full record

Trial reportThe Journal of international medical research2016

Efficacy of intrathecal morphine for postoperative pain management following open nephrectomy.

Hyun-Chang Kim, Jun-Yeol Bae, Tae Kyong Kim, Yunseok Jeon, Jeong Jin Min, Eui-Kyoung Goo, Deok Man Hong

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in The Journal of international medical research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.

  1. Pooled it
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  3. Review
  4. Article
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  10. In Reply.Stem cells translational medicine · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Hyun-Chang KimDepartment of Anaesthesiology and Pain Medicine, Keimyung University, School of Medicine, Daegu, Korea.
Jun-Yeol BaeDepartment of Anaesthesiology and Pain Medicine, Seoul National University Hospital, Seoul, Korea.
Tae Kyong KimDepartment of Anaesthesiology and Pain Medicine, Seoul National University Hospital, Seoul, Korea.
Yunseok JeonDepartment of Anaesthesiology and Pain Medicine, Seoul National University Hospital, Seoul, Korea.
Jeong Jin MinDepartment of Anaesthesiology and Pain Medicine, Samsung Medical Center, Seoul, Korea.
Eui-Kyoung GooDepartment of Anaesthesiology and Pain Medicine, The Armed Forces Medical Command, Seongnam, Korea.
Deok Man HongDepartment of Anaesthesiology and Pain Medicine, Seoul National University Hospital, Seoul, Korea mellyn7@gmail.com.
Seoul National University Hospital · KRArmed Forces Capital Hospital · KRKeimyung University · KRSamsung Medical Center · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the efficacy and safety of intrathecal morphine (ITM) for postoperative pain control in patients with renal cell carcinoma undergoing open nephrectomy.

methodsForty-five patients scheduled for open nephrectomy were randomised to receive 300 µg ITM and intravenous patient-controlled analgesia (IV-PCA) (n = 22) or IV-PCA alone (n = 23) for postoperative analgesia. The numeric pain score (NPS), postoperative IV-PCA requirements and opioid-related complications including nausea, vomiting, dizziness, headache, and pruritus were compared between groups.

resultsNPS was significantly lower in the ITM group up to 24 h postoperatively. Upon coughing, NPS at 24 h postoperatively was 50 (interquartile range (IQR) 30-60) in the ITM group and 60 (45-70) in the IV-PCA group. Cumulative morphine consumption at 72 h postoperatively was significantly lower in the ITM group compared with the IV-PCA group (20 (9-33) mg vs. 31 (21-49) mg, respectively). Opioid-related complications were similar in both groups with the exception of pruritus (ITM, 77% vs. IV-PCA, 26%).

conclusionsITM was associated with greater analgesia without serious complications in patients undergoing open nephrectomy.

Indexed as

Injections, SpinalAnalgesia, Patient-ControlledCarcinoma, Renal CellDemographyHumansKidney NeoplasmsMorphineNephrectomyPostoperative PainMorphineInjectionsmorphinenephrectomypainpostoperativespinal

Identifiers

PMID26689781
PMCPMC5536567
OpenAlexW2277023021

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.