Evidence map›Paper›PMID 26689691›Full record

ReviewTopics in spinal cord injury rehabilitation2015

Measurement of Bone: Diagnosis of SCI-Induced Osteoporosis and Fracture Risk Prediction.

Karen L Troy, Leslie R Morse

Open access · bronzeAbstract readReview
In one paragraph

Review in Topics in spinal cord injury rehabilitation, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. Don't be sidelined: Winning strategies for care of the para athlete.Bulletin of the Hospital for Joint Disease (2013) · 2025
    Review
  3. Article
  4. International Spinal Cord Injury Fracture History Extended Data Set.Topics in spinal cord injury rehabilitation · 2025
    Article
  5. Article
  6. Article
  7. Functional electrical stimulation (FES)-assisted rowing combined with zoledronic acid, but not alone, preserves distal femur strength and stiffness in people with chronic spinal cord injury.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2021
    Article
  8. Article
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  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Analysis of the evolution of cortical and trabecular bone compartments in the proximal femur after spinal cord injury by 3D-DXA.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2018
    Observational
  18. Article
  19. Bone loss at the distal femur and proximal tibia in persons with spinal cord injury: imaging approaches, risk of fracture, and potential treatment options.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2017
    Review
  20. Dual-energy X-ray absorptiometry and fracture prediction in patients with spinal cord injuries and disorders.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Karen L TroyDepartment of Biomedical Engineering, Worcester Polytechnic Institute, Worcester, Massachusetts.
Leslie R MorseSpaulding-Harvard SCI Model System, Spaulding Rehabilitation Hospital, Boston, Massachusetts.
Harvard University · USWorcester Polytechnic Institute · US

Funding

Adiposity and Bone Loss in Spinal Cord InjuryR01AR059270 · NIAMS · SPAULDING REHABILITATION HOSPITAL · PI MORSE, LESLIE R. · 2010 to 2014
$3.0M
NIAMS NIH HHS AR059270NIAMS NIH HHS L30 AR063489NIAMS NIH HHS R01 AR059270NICHD NIH HHS HD056721NICHD NIH HHS L30 HD056721
6 · The paper itself

Abstract

backgroundSpinal cord injury (SCI) is associated with a rapid loss of bone mass, resulting in severe osteoporosis and a 5- to 23-fold increase in fracture risk. Despite the seriousness of fractures in SCI, there are multiple barriers to osteoporosis diagnosis and wide variations in treatment practices for SCI-induced osteoporosis.

methodsWe review the biological and structural changes that are known to occur in bone after SCI in the context of promoting future research to prevent or reduce risk of fracture in this population. We also review the most commonly used methods for assessing bone after SCI and discuss the strengths, limitations, and clinical applications of each method.

conclusionsAlthough dual-energy x-ray absorptiometry assessments of bone mineral density may be used clinically to detect changes in bone after SCI, 3-dimensional methods such as quantitative CT analysis are recommended for research applications and are explained in detail.

Indexed as

Bone DensityAbsorptiometry, PhotonBone and BonesFractures, BoneHumansOsteoporosisSpinal Cord InjuriesTomography, X-Ray Computedbone densityfinite element analysisfractureosteoporosisQCTrehabilitation medicinespinal cord injury

Identifiers

PMID26689691
PMCPMC4750811
OpenAlexW2240063503

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.