ArticleThe Clinical neuropsychologist2015
Memory Similarities Between Essential Tremor and Parkinson's Disease: A Final Common Pathway?
Article in The Clinical neuropsychologist, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Korean Red Ginseng Attenuates Dysfunctions and Modulates Inflammatory and Neuroplasticity Markers in the Harmaline-Induced Model of Essential Tremor.Brain and behavior · 2026Article
- Modulation of Lingo-1 and NMDA receptor expression by memantine and vitamin D3 co-therapy attenuates motor and non-motor symptoms in essential tremor.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- Screening for a "trifecta" of executive function patterns in a large cohort of individuals with Parkinson's disease.Journal of the International Neuropsychological Society : JINS · 2025Article
- Social cognitive impact of essential tremor.Scientific reports · 2025Article
- Negative emotion modulates postural tremor variability in Parkinson's disease: A multimodal EEG and motion sensor study toward behavioral interventions.IBRO neuroscience reports · 2025Article
- Essential Tremor and Mortality in Older Adults: The Role of Word Recall, a Measure of Episodic Memory, in a 23-Year Follow-Up Study.Journal of clinical medicine · 2025Article
- Clinical Features of Essential Tremor and its Impact on Quality of Life in Japan.Tremor and other hyperkinetic movements (New York, N.Y.) · 2025Article
- Perception of cognitive change by individuals with Parkinson's disease or essential tremor seeking deep brain stimulation: Utility of the cognitive change index.Journal of the International Neuropsychological Society : JINS · 2024Article
- Differential contributions of depression, apathy, and anxiety to neuropsychological performance in Parkinson's disease versus essential tremor.Journal of clinical and experimental neuropsychology · 2022Article
- Cognitive subtypes in individuals with essential tremor seeking deep brain stimulation.The Clinical neuropsychologist · 2022Article
- Essential tremor and cognitive impairment: who, how, and why.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022Review
- Article
- Statistically Defined Parkinson's Disease Executive and Memory Cognitive Phenotypes: Demographic, Behavioral, and Structural Neuroimaging Comparisons.Journal of Parkinson's disease · 2021Article
- Mind the gaps: What we don't know about cognitive impairment in essential tremor.Parkinsonism & related disorders · 2019Review
- Symptom Dimensions of Depression and Apathy and Their Relationship With Cognition in Parkinson's Disease.Journal of the International Neuropsychological Society : JINS · 2018Article
- Mild Cognitive Impairment Subtypes in a Cohort of Elderly Essential Tremor Cases.Journal of the International Neuropsychological Society : JINS · 2017Article
- Emotion modulation of the startle reflex in essential tremor: Blunted reactivity to unpleasant and pleasant pictures.Parkinsonism & related disorders · 2017Article
- Diagnostic performance of essential tremor criteria in electronic health records: a retrospective neurology cohort study.Frontiers in neurologyArticle
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Authors and funding
6 authors.
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Abstract
objectiveA growing body of literature supports the view that essential tremor (ET) involves alteration of cerebellar-thalamo-cortical networks which can result in working memory and executive deficits. In this study, we tested the hypothesis that individuals with ET would exhibit worse performance on memory tasks requiring more intrinsic organization and structuring (i.e., word lists) relative to those with fewer 'executive' demands (i.e., stories), similar to that previously observed in individuals with Parkinson's disease (PD).
methodParticipants included a convenience sample of 68 ET patients and 68 idiopathic PD patients, retrospectively matched based on age, education, and sex. All patients underwent routine neuropsychological evaluation assessing recent memory, auditory attention/working memory, language, and executive function. Memory measures included the Hopkins Verbal Learning Test-R and WMS-III Logical Memory.
resultsBoth ET and PD patients performed significantly worse on word list than story memory recall tasks. The magnitude of the difference between these two memory tasks was similar for ET and PD patients. In both patient groups, performance on measures of executive function and auditory attention/working memory was not distinctly correlated with word list vs. story recall.
conclusionsThese findings suggest that frontal-executive dysfunction in both ET and PD may negatively influence performance on memory tests that are not inherently organized. Although the pathophysiology of these two 'movement disorders' are quite distinct, both have downstream effects on thalamo-frontal circuitry which may provide a common pathway for a similar memory phenotype. Findings are discussed in terms of neuroimaging evidence, conceptual models, and best practice.
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