Evidence map›Paper›PMID 26689304›Full record

Trial reportJournal of consulting and clinical psychology2016

Predictors and moderators of treatment outcome in a randomized clinical trial for adults with symptoms of bulimia nervosa.

Erin C Accurso, Stephen A Wonderlich, Ross D Crosby, Tracey L Smith, Marjorie H Klein, James E Mitchell, Scott J Crow, Kelly C Berg, Carol B Peterson

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of consulting and clinical psychology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
6.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 53 citations in OpenAlex.

  1. Trial
  2. An exploratory investigation of predictors of outcome in face-to-face and online cognitive-behavioural therapy for bulimia nervosa.European eating disorders review : the journal of the Eating Disorders Association · 2022
    Trial
  3. Trial
  4. Trial
  5. The current clinical approach to feeding and eating disorders aimed to increase personalization of management.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2025
    Article
  6. Review
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  16. Article
  17. Emerging Psychological Treatments in Eating Disorders.The Psychiatric clinics of North America · 2019
    Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Erin C AccursoDepartment of Psychiatry, University of California, San Francisco.
Stephen A WonderlichNeuropsychiatric Research Institute.
Ross D CrosbyNeuropsychiatric Research Institute.
Tracey L SmithBaylor College of Medicine.
Marjorie H KleinDepartment of Psychiatry, University of Wisconsin, Madison.
James E MitchellNeuropsychiatric Research Institute.
Scott J CrowUniversity of Minnesota Medical School.
Kelly C BergUniversity of Minnesota Medical School.
Carol B PetersonUniversity of Minnesota Medical School.
Neuropsychiatric Research Institute · USUniversity of Minnesota Medical Center · USBaylor College of Medicine · USUniversity of California, San Francisco · USUniversity of Wisconsin–Madison · US

Funding

Obesity and Energy Metabolism CoreP30DK050456 · NIDDK · UNIVERSITY OF MINNESOTA TWIN CITIES · PI BERNLOHR, DAVID A · 1995 to 2015
$17.0M
Regional Postdoctoral Training Grant in Eating Disorders ResearchT32MH082761 · NIMH · UNIVERSITY OF MINNESOTA · PI CAROL B. PETERSON · 2009 to 2026
$6.2M
The Treatment of Binge Eating DisorderR01DK061912 · NIDDK · UNIVERSITY OF MINNESOTA TWIN CITIES · PI CROW, SCOTT J · 2002 to 2004
$868k
Integrative Cognitive-Affective Therapy for Bulimia NervosaR34MH077571 · NIMH · SANFORD RESEARCH NORTH · PI WONDERLICH, STEPHEN ARTHUR · 2007 to 2009
$590k
NIDDK NIH HHS P30 DK050456NIDDK NIH HHS P30DK50456NIDDK NIH HHS R01 DK061912NIDDK NIH HHS R01DK61912NIMH NIH HHS R34 MH077571NIMH NIH HHS R34MH077571NIMH NIH HHS T32 MH082761NIMH NIH HHS T32MH082761
6 · The paper itself

Abstract

objectiveThis study examined predictors and moderators of outcome in 2 treatments for bulimia nervosa (BN).

methodEighty adults with BN symptoms at 1 of 2 sites were randomized to 21 sessions of integrative cognitive-affective therapy for BN (ICAT-BN) or enhanced cognitive behavior therapy (CBT-E). Generalized linear models examined predictors and moderators of improvements in bulimic behavior and eating disorder psychopathology at end of treatment (EOT) and 4-month follow-up (FU).

resultsAt EOT, individuals with higher dietary restraint had greater reductions in bulimic behavior. At FU, individuals with higher weight and shape concern had greater reductions in bulimic behavior, whereas those with greater baseline depression had less improvement in eating disorder psychopathology. Individuals higher in stimulus seeking had greater reductions in bulimic behavior and eating disorder psychopathology at follow up in ICAT-BN than in CBT-E, whereas individuals lower in stimulus seeking had greater reductions in bulimic behavior in CBT-E than in ICAT-BN. Finally, individuals with higher affective lability had greater reductions in eating disorder psychopathology in ICAT-BN than in CBT-E, whereas improvements were comparable across treatments for individuals with lower affective lability.

conclusionsThis study identified 3 nonspecific predictors of outcome (i.e., dietary restraint, weight and shape concern, and depression) and 2 moderators (i.e., affective lability and stimulus seeking). All moderator effects emerged at FU rather than at EOT, suggesting that the moderating effects of treatment were not immediately apparent. These results suggest that individuals with higher affective lability and stimulus seeking may benefit more from treatment with a greater focus on affective states and self-regulation.

Indexed as

AdultAffectBody ImageBulimia NervosaCognitive Behavioral TherapyDepressionFemaleHumansMaleOutcome Assessment, Health Care

Identifiers

PMID26689304
PMCPMC4738019
OpenAlexW2362265798

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.