Evidence map›Paper›PMID 26688435›Full record

Trial reportLipids2016

Enhanced Bioavailability of EPA From Emulsified Fish Oil Preparations Versus Capsular Triacylglycerol.

Susan K Raatz, LuAnn K Johnson, Michael R Bukowski

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Lipids, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 21 citations in OpenAlex.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Susan K RaatzARS, USDA, Grand Forks Human Nutrition Research Center, 2420 2nd Avenue North, Grand Forks, ND, 58203, USA. susan.raatz@ars.usda.gov.
LuAnn K JohnsonARS, USDA, Grand Forks Human Nutrition Research Center, 2420 2nd Avenue North, Grand Forks, ND, 58203, USA.
Michael R BukowskiARS, USDA, Grand Forks Human Nutrition Research Center, 2420 2nd Avenue North, Grand Forks, ND, 58203, USA.
Grand Forks Human Nutrition Research Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

For those individuals who are unable to consume adequate long chain omega-3 fatty acids (LCn3) from dietary sources, fish oil supplementation is an attractive alternative Pre-emulsified fish oil supplements, an alternative to capsular triacylglycerol, may enhance the uptake of LCn3 fatty acids it contains. A randomized, Latin-square crossover design was used to compare the effects of four fish oil supplement preparations (Emulsions S, B and N) on phospholipid fatty acid (PLFA) concentrations in ten healthy volunteers compared to oil capsules over 48 h after a single dose and chylomicron fatty acid (CMFA) was evaluated over 8 h. Blood samples were collected at 0, 2, 4, 8, 24 and 48 h and fatty acid concentrations of PLFA and CMFA were determined by gas chromatography and the integrated area under the curve over 40 h (iAUC0-48) was determined. Emulsion S and Emulsion N promoted increased uptake of EPA into PLFA over 48 h when evaluating by iAUC0-48 or individual time points of assessment. No differences were observed between supplements in the CMFA concentrations.

Indexed as

Dietary SupplementsAdultBiological AvailabilityCapsulesChylomicronsEicosapentaenoic AcidEmulsionsFatty AcidsFemaleFish OilsHumansMalePhospholipidsTriglyceridesCapsulesChylomicronsEicosapentaenoic AcidEmulsionsFatty AcidsFish OilsPhospholipidsTriglyceridesChylomicronsFish oilPhospholipid fatty acids

Identifiers

PMID26688435
OpenAlexW2257214969

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.