ArticleResuscitation2016
The association between post resuscitation hemoglobin level and survival with good neurological outcome following Out Of Hospital cardiac arrest.
Article in Resuscitation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Hemoglobin as a prognostic marker for neurological outcomes in post-cardiac arrest patients: a meta-analysis.Scientific reports · 2023Pooled it
- Hemoglobin trends and transfusion practices after cardiac arrest: a cohort study.Journal of intensive care · 2026Article
- Article
- Prognostic value of initial hemoglobin levels for neurological outcomes in patients with out-of-hospital cardiac arrest in South Korea.Acute and critical care · 2026Article
- Association between early red blood cell transfusion after return of spontaneous circulation and clinical outcomes in cardiac arrest patients.Scientific reports · 2026Article
- Survival Prediction for Non-Asphyxia-Related Hypothermic Cardiac Arrest Patients After Extracorporeal Rewarming: Development of the HELP Score.ASAIO journal (American Society for Artificial Internal Organs : 1992) · 2026Article
- The "SOOTEST-ICU" bundle for optimizing cerebral hypoxia and reperfusion to minimize brain injury after resuscitation from cardiac arrest.World journal of emergency medicine · 2025Article
- Optimizing brain protection after cardiac arrest: advanced strategies and best practices.Interface focus · 2024Review
- Mechanisms and treatment of anemia related to cardiac arrest.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2024Review
- Neuromonitoring after Pediatric Cardiac Arrest: Cerebral Physiology and Injury Stratification.Neurocritical care · 2024Review
- Critical Care Management of Patients After Cardiac Arrest: A Scientific Statement from the American Heart Association and Neurocritical Care Society.Neurocritical care · 2024Article
- Critical Care Management of Patients After Cardiac Arrest: A Scientific Statement From the American Heart Association and Neurocritical Care Society.Circulation · 2024Review
- Anemia before in-hospital cardiac arrest and survival from cardio-pulmonary resuscitation-a retrospective cohort study.Journal of anesthesia, analgesia and critical care · 2022Article
- Enhancing cardiac arrest survival with extracorporeal cardiopulmonary resuscitation: insights into the process of death.Annals of the New York Academy of Sciences · 2022Review
- Monitoring and modifying brain oxygenation in patients at risk of hypoxic ischaemic brain injury after cardiac arrest.Critical care (London, England) · 2021Review
- Change of Hemoglobin Levels in the Early Post-cardiac Arrest Phase Is Associated With Outcome.Frontiers in medicine · 2021Article
- Glycated Hemoglobin is Associated with Glycemic Control and 6-Month Neurologic Outcome in Cardiac Arrest Survivors Undergoing Therapeutic Hypothermia.Neurocritical care · 2020Article
- Extracorporeal membrane oxygenation mitigates myocardial injury and improves survival in porcine model of ventricular fibrillation cardiac arrest.Scandinavian journal of trauma, resuscitation and emergency medicine · 2019Article
- Hemoglobin concentration is associated with neurologic outcome after cardiac arrest in patients treated with targeted temperature management.Clinical and experimental emergency medicine · 2018Article
- The association between hemoglobin concentration and neurologic outcome after cardiac arrest.Journal of critical care · 2016Observational
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
aimsto explore the association between post return of spontaneous circulation (ROSC) hemoglobin level and survival with good neurological outcome following out-of-hospital cardiac arrest.
methodsWe studied adults with non-traumatic out-of-hospital cardiac arrest who achieved ROSC within 50min of collapse. We quantified the association between post ROSC hemoglobin level and good neurological outcome (defined as Cerebral Performance Category score of 1or 2), using multivariate logistic regression analyses. The impact of Post ROSC hemoglobin level ≥10gdl(-1) and time varying hemoglobin level ≥10gdl(-1) on time to Survival with good outcome was assessed using Cox proportional hazard models.
resultsOf 931 cardiac arrest patients, 146 (16%) achieved ROSC and 30 survived to discharge with a good neurological outcome. Of those with post ROSC hemoglobin level ≥10gdl(-1), 28% (27/98) had good outcome, whereas of those with level <10mgdl(-1) only 6% (3/48) had good outcome (CPC<3, P=0.003). The use of blood transfusions and therapeutic hypothermia were comparable in both good and bad outcome groups. An immediate post ROSC hemoglobin level ≥10gdl(-1) was significantly associated with good neurological outcome (AOR 8.31 95% CI 1.89-36.52 P=0.005). Patients with post ROSC hemoglobin ≥10gdl(-1) were more likely to achieve good outcome earlier (HR 6.02 95% CI 1.75-20.72 P=0.004).
conclusionsPost ROSC hemoglobin level ≥10gdl(-1) is associated with survival with good neurological outcome. The importance of time to achieve such level and the role of blood transfusion warrants further investigation.
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