Evidence map›Paper›PMID 26687186›Full record

ArticleMolecular neurobiology2016

Attenuating Ischemic Disruption of K

Dongman Chao, Qinyu Wang, Gianfranco Balboni, Guanghong Ding, Ying Xia

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular neurobiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
4.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Condition-specific transcriptional regulation of neuronal ion channel genes in brain ischemia.International journal of physiology, pathophysiology and pharmacology · 2017
    Article
  8. Article
  9. Delta Opioids: Neuroprotective Roles in Preclinical Studies.Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Dongman ChaoDepartment of Neurosurgery, The University of Texas Medical School at Houston, Houston, TX, 77030, USA.
Qinyu WangDepartment of Neurosurgery, The University of Texas Medical School at Houston, Houston, TX, 77030, USA.
Gianfranco BalboniDepartment of Life and Environmental Sciences, University of Cagliari, Cagliari, Italy.
Guanghong DingShanghai Research Center for Acupuncture and Meridians, Guoshoujing Rd 199, Shanghai, 201203, People's Republic of China.
Ying XiaDepartment of Neurosurgery, The University of Texas Medical School at Houston, Houston, TX, 77030, USA. Ying.Xia@uth.tmc.edu.
Shanghai Research Center for Acupuncture and Meridians · CNUniversity of Cagliari · IT

Funding

Hypoxia &Neuronal Excitability: Cellular MechanismsR01HD034852 · NICHD · YALE UNIVERSITY · PI XIA, YING · 1997 to 2012
$3.5M
A new strategy for protection from cerebral ischemiaR01AT004422 · NCCIH · YALE UNIVERSITY · PI XIA, YING · 2009 to 2013
$1.9M
NCCIH NIH HHS R01 AT004422NICHD NIH HHS R01 HD034852
6 · The paper itself

Abstract

Perinatal hypoxic-ischemic (HI) brain injury results in death or profound long-term neurologic disability in both children and adults. However, there is no effective pharmacological therapy due to a poor understanding of HI events, especially the initial triggers for hypoxic-ischemic injury such as disrupted ionic homeostasis and the lack of effective intervention strategy. In the present study, we showed that neonatal brains undergo a developmental increase in the disruption of K

Indexed as

Acupuncture TherapyHomeostasisAnimalsAnimals, NewbornCerebral CortexFemaleGlucoseHypoxia-Ischemia, BrainOxygenPotassiumRats, Sprague-DawleyReceptors, Opioid, deltaGlucoseOxygenPotassiumReceptors, Opioid, deltaAcupunctureCortexK+ homeostasisNeonatal hypoxia-ischemiaNeuroprotectionδ-opioid receptor

Identifiers

PMID26687186
OpenAlexW2214560675

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.