ArticleThe European physical journal. E, Soft matter2015
A nonequilibrium power balance relation for analyzing dissipative filament dynamics.
Article in The European physical journal. E, Soft matter, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Label-free Imaging and Bending Analysis of Microtubules by ROCS Microscopy and Optical Trapping.Biophysical journal · 2018Article
- Single microtubules and small networks become significantly stiffer on short time-scales upon mechanical stimulation.Scientific reports · 2017Article
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Authors and funding
3 authors.
Funding
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Abstract
Biofilaments like F-actin or microtubules, as well as cilia, flagella, or filament bundles, are often deformed by distributed and time-dependent external forces. It is highly desirable to characterize these filaments' mechanics in an efficient way, either using a single experiment or a high throughput method. We here propose a dynamic power balance approach to study nonequilibrium filament dynamics and exemplify it both experimentally and theoretically by applying it to microtubule gliding assay dynamics. Its usefulness is highlighted by the experimental determination of the lateral friction coefficient for microtubules on kinesins. In contrast to what is usually assumed, friction is anisotropic, in a similar fashion as hydrodynamic friction. We also exemplify, by considering a microtubule buckling event, that if at least one parameter is known in advance, all other parameters can be determined by analyzing a single time-dependent experiment.
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Registered trials
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