SynthesisScientific reports2015
Associations of Different Adipose Tissue Depots with Insulin Resistance: A Systematic Review and Meta-analysis of Observational Studies.
Synthesis in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 98 papers.
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Who cites it
98 citing papers in PubMed.
- Achieving Diabetes Remission Through Dietary Intervention: A 12-Month Randomized Controlled Trial of Caloric-Carbohydrate Restriction in Overweight Patients With Early-Stage Type 2 Diabetes Mellitus.Journal of diabetes research · 2026Trial
- Weight Changes Are Linked to Adipose Tissue Genes in Overweight Women with Polycystic Ovary Syndrome.International journal of molecular sciences · 2024Trial
- Effects of a low-carbohydrate ketogenic diet on health parameters in resistance-trained women.European journal of applied physiology · 2021Trial
- Exercise Dose Effects on Body Fat 12 Months after an Exercise Intervention: Follow-up from a Randomized Controlled Trial.Journal of obesity · 2019Trial
- Associations and Discriminatory Performance of Anthropometric and Body-Shape Indices for Identifying Hypertension in Adults with Type 2 Diabetes in Malawi: A Cross-Sectional Study.Diagnostics (Basel, Switzerland) · 2026Article
- Pooled two-cohort MRI body composition phenotyping with open-source deep learning.Communications medicine · 2026Article
- CAN the variants in the THADA and ADAMST9 genes be common risk factors for type 2 diabetes development and obesity.Molecular biology reports · 2026Article
- Plasma Amino Acid Responses to an Oral Glucose Challenge Relate More Strongly to Body Adiposity Than to Insulin Resistance.bioRxiv : the preprint server for biology · 2026Article
- White adipose tissue expansion as the driver of insulin resistance and secondary endocrine disturbances in obesity- a narrative review.Diabetology & metabolic syndrome · 2026Review
- Comparative Analysis of Dietary Patterns in Children With Phenylketonuria Phenotypes and Controls: Implications for Nutritional Status.Journal of inherited metabolic disease · 2026Article
- Physical Activity, Metabolic Dysfunction, and the Kynurenine Pathway in Endometriosis and Polycystic Ovary Syndrome: A Literature Review.Biomolecules · 2026Review
- Visceral adiposity, metabolic health and aging.Nature aging · 2026Review
- Impact of Menopausal Status and Female Reproductive Aging on the Outcomes of Bariatric Surgery: A Narrative Review.Cureus · 2026Review
- Behavioral and dietary determinants of central adiposity assessed by ABSI in a mediterranean clinical sample.Public health nutrition · 2025Article
- Associations between asprosin, insulin resistance, and oxidative stress in adults with obesity.Scientific reports · 2025Article
- Is Type 2 Diabetes a Modifiable Risk Factor for the Evolution and Progression of Heart Failure With a Preserved Ejection Fraction?Journal of the American College of Cardiology · 2025Review
- Which insulin resistance indices best predict future frailty progression in a cardiovascular-kidney-metabolic syndrome stage 0-3 population: a national prospective cohort and machine learning study.Diabetology & metabolic syndrome · 2025Article
- Postprandial exercise attenuates glucose and insulin and is associated with age, cognitive function, and extracellular/intracellular body water.Physiological reports · 2025Article
- Central Obesity Disrupts Brain Network Organization in Aging via Metabolic and Structural Pathways.Aging and disease · 2025Article
- Visceral Fat As The Main Obesity Index That Determines The Occurrence of Adipose Tissue Insulin Resistance.EJIFCC · 2025Article
38 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fat distribution is strongly associated with insulin resistance, a risk factor for type 2 diabetes and cardiovascular diseases. However, associations of different adipose tissue depots or/and obesity indices with insulin resistance have not been systematically evaluated. In this study we examined associations of different adipose tissue depots/obesity indices with insulin resistance, as measured by homeostatic model assessment of insulin resistance (HOMA-IR) in observational studies. A total of 40 studies with 56 populations and 29 adipose tissue depots/obesity indices were included in the meta-analysis. There were strong correlation between HOMA-IR and visceral fat mass (r = 0.570, 95% confidence interval(CI): 0.424~0.687), total fat mass (r = 0.492, 95%CI: 0.407~0.570), body mass index (r = 0.482, 95%CI: 0.445~0.518) and waist circumference (r = 0.466, 95%CI: 0.432~0.500), except lower extremity fat (r = 0.088, 95%CI: -0.116~0.285). Sample size, diabetic status, gender, mean of body mass index, and race contributed to heterogeneity of these associations. This study showed a positive correlation between insulin resistance and most adipose tissue depots/obesity indices, and the strongest association is for visceral fat mass.
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