ArticleExperimental brain research2016
Delayed grip relaxation and altered modulation of intracortical inhibition with aging.
Article in Experimental brain research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed, 13 citations in OpenAlex.
- Beyond grip strength: selective slowing of grip force release but not initiation dynamics in a go/no-go target force-matching task.Frontiers in aging neuroscience · 2026Article
- Task-dependent frequency of intermuscular coherence in the presence of transcutaneous electrical spinal cord stimulation: a feasibility study.Frontiers in human neuroscience · 2025Article
- Defining Normal Sequential Swallowing Biomechanics.Dysphagia · 2023Article
- Associating Functional Neural Connectivity and Specific Aspects of Sensorimotor Control in Chronic Stroke.Sensors (Basel, Switzerland) · 2023Article
- The effect of initiation prediction and non-prediction on muscle relaxation control.Journal of physical therapy science · 2023Article
- Shoulder position and handedness differentially affect excitability and intracortical inhibition of hand muscles.Experimental brain research · 2021Article
- Older Compared With Younger Adults Performed 467 Fewer Sit-to-Stand Trials, Accompanied by Small Changes in Muscle Activation and Voluntary Force.Frontiers in aging neuroscience · 2021Article
- Task-related measures of short-interval intracortical inhibition and GABA levels in healthy young and older adults: A multimodal TMS-MRS study.NeuroImage · 2020Article
- Strategies to Reduce Fall Severity after a Perturbation during Ladder Climbing.IISE transactions on occupational ergonomics and human factorsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
Grip relaxation is a voluntary action that requires an increase in short-interval intracortical inhibition (SICI) in healthy young adults, rather than a simple termination of excitatory drive. The way aging affects this voluntary inhibitory action and timing of grip relaxation is currently unknown. The objective of this study was to examine aging-related delays in grip relaxation and SICI modulation for the flexor digitorum superficialis muscle during grip relaxation. The main finding was that young adults increased SICI to relax their grips, whereas older adults did not increase SICI with a prolonged grip relaxation time (p < 0.05 for both SICI modulation and grip relaxation time). A secondary experiment showed that both young and older adults did not change H reflex excitability during grip relaxation. Our data suggest that grip relaxation is mediated by increased cortical inhibitory output in young adults, and aging-related impairment in increasing cortical inhibitory output may hamper timely cessation of muscle activity. Our data also suggest a lesser role of the spinal circuits in grip muscle relaxation. This knowledge may contribute to understanding of aging-related movement deterioration and development of interventions for improving modulation of SICI to improve muscle relaxation and movement coordination.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.