Evidence map›Paper›PMID 26686048›Full record

ArticleDiabetes research and clinical practice2016

Fasting and 2-hour plasma glucose, and HbA1c in pregnancy and the postpartum risk of diabetes among Chinese women with gestational diabetes.

Huikun Liu, Shuang Zhang, Leishen Wang, Junhong Leng, Weiqin Li, Nan Li, Min Li, Yijuan Qiao, Huiguang Tian, Jaakko Tuomilehto and 3 more

Abstract read
In one paragraph

Article in Diabetes research and clinical practice, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
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  8. Prevalence and Metabolic Predictors for Early Diagnosed Prediabetes in Women with Previous Gestational Diabetes: Observational Cohort Study.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 6 countries.

Huikun LiuTianjin Women's and Children's Health Center, 96 Guizhou Road, Heping District, Tianjin 300070, China.
Shuang ZhangTianjin Women's and Children's Health Center, 96 Guizhou Road, Heping District, Tianjin 300070, China.
Leishen WangTianjin Women's and Children's Health Center, 96 Guizhou Road, Heping District, Tianjin 300070, China.
Junhong LengTianjin Women's and Children's Health Center, 96 Guizhou Road, Heping District, Tianjin 300070, China.
Weiqin LiTianjin Women's and Children's Health Center, 96 Guizhou Road, Heping District, Tianjin 300070, China.
Nan LiTianjin Women's and Children's Health Center, 96 Guizhou Road, Heping District, Tianjin 300070, China.
Min LiTianjin Women's and Children's Health Center, 96 Guizhou Road, Heping District, Tianjin 300070, China.
Yijuan QiaoTianjin Women's and Children's Health Center, 96 Guizhou Road, Heping District, Tianjin 300070, China.
Huiguang TianTianjin Women's and Children's Health Center, 96 Guizhou Road, Heping District, Tianjin 300070, China.
Jaakko TuomilehtoDepartment of Public Health, University of Helsinki, Helsinki, Finland; Centre for Vascular Prevention, Danube-University Krems, 3500 Krems, Austria; Department of Chronic Disease Prevention, National Institute for Health and Welfare, 00271 Helsinki, Finland; Diabetes Research Group, King Abdulaziz University, 21589 Jeddah, Saudi Arabia.
Xilin YangDepartment of Epidemiology and Biostatistics, Tianjin Medical University, 22 Qixiangtai Road, Heping district, Tianjin 300070, China.
Zhijie YuPopulation Cancer Research program, Dalhousie University, 6299 South Street, Halifax, NS, Canada B3H 4R2.
Gang HuPennington Biomedical Research Center, 6400 Perkins Road, Baton Rouge, LA 70808, USA. Electronic address: gang.hu@pbrc.edu.
Tianjin Children's Hospital · CNDalhousie University · CAFinnish Institute for Health and Welfare · FIPennington Biomedical Research Center · USTianjin Medical University · CN

Funding

Methylomics of prenatal GDM: Natural history & lifestyle intervention in childrenR01DK100790 · NIDDK · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI BACCARELLI, ANDREA, HOU, LIFANG · 2014 to 2017
$2.6M
NIDDK NIH HHS R01 DK100790NIDDK NIH HHS R01DK100790
6 · The paper itself

Abstract

aimsVery few studies have assessed the association of fasting and 2h glucose, and HbA1c during pregnancy with postpartum diabetes risk among women with prior gestational diabetes mellitus (GDM). We assessed the association of fasting glucose, 2h glucose and HbA1c at 26-30 gestational weeks with postpartum diabetes risk among women with prior GDM.

methodsA cohort study in 1263 GDM women at 1-5 years after delivery was performed. Cox proportional hazards regression models were used to evaluate the association of fasting and 2h plasma glucose, and HbA1c at 26-30 gestational weeks with the risk of diabetes at postpartum.

resultsThe multivariable-adjusted (age, pre-pregnancy body mass index, weight gain during pregnancy, current body mass index, family history of diabetes, marital status, education, family income, smoking status, passive smoking, leisure-time physical activity, alcohol drinking, and intake of energy, saturated fat, and dietary fiber) hazard ratios of postpartum diabetes were 1.61 (95% confidence interval [CI]: 1.36-1.91) for each 1 mmol/l increase in fasting glucose during pregnancy, 1.63 (95% CI: 1.45-1.84) for each 1 mmol/l increase in 2h glucose during pregnancy, 2.11 (95% CI: 1.50-2.97) for each 1 unit (%) increase in HbA1c during pregnancy. When fasting glucose, 2h glucose and HbA1c during pregnancy were entered multivariable-adjusted model simultaneously, 2h glucose and HbA1c but not fasting glucose remained to be significant and positive predictors for postpartum diabetes.

conclusionsFor women with prior GDM, 2h plasma glucose and HbA1c during pregnancy are independent predictors of postpartum diabetes, but fasting plasma glucose during pregnancy is not.

Indexed as

AdultBlood GlucoseBody Mass IndexChinaCohort StudiesDiabetes, GestationalDiabetes MellitusFastingFemaleFollow-Up StudiesGlycated HemoglobinHumansIncidencePostpartum PeriodPregnancyTime FactorsBlood GlucoseGlycated Hemoglobinhemoglobin A1c protein, humanFasting plasma glucoseGestational diabetesHbA1cPostpartum diabetesPregnancy

Identifiers

PMID26686048
PMCPMC4753114
OpenAlexW2175492097

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.