Evidence map›Paper›PMID 26686037›Full record

ArticleThe Lancet. Haematology2015

G6PD deficiency: a polymorphism balanced by heterozygote advantage against malaria.

Lucio Luzzatto

Abstract readComment
PubMed Publisher
In one paragraph

Article in The Lancet. Haematology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. No G6PD A- (G202A) variant detected amongMalariaWorld journal · 2026
    Article
  6. Article
  7. Pathogens (Basel, Switzerland) · 2023
    Article
  8. Article
  9. Diagnosis and clinical management of enzymopathies.Hematology. American Society of Hematology. Education Program · 2021
    Article
  10. Article
  11. Article
  12. Article
  13. Optimizing G6PD testing forWellcome open research · 2020
    Review
  14. Review
  15. Article
  16. Article
  17. Observational
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Lucio LuzzattoDeptartment of Haematology, Muhimbili University Hospital, Dar es Salaam, Tanzania; Istituto Toscano Tumori, Florence, Italy. Electronic address: lucio.luzzatto@ittumori.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Glucosephosphate Dehydrogenase DeficiencyHeterozygoteGlucosephosphate DehydrogenaseHumansMalariaPolymorphism, GeneticGlucosephosphate Dehydrogenase

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.