ReviewCurrent gastroenterology reports2016
Ineffective Esophageal Motility (IEM): the Old-New Frontier in Esophagology.
Review in Current gastroenterology reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 56 citations in OpenAlex.
- Long-term Prognosis and Prognostic Factors in Ineffective Esophageal Motility.Journal of neurogastroenterology and motility · 2025Article
- Comparative Prevalence of Ineffective Esophageal Motility: Impact of Chicago v4.0 vs. v3.0 Criteria.Medicina (Kaunas, Lithuania) · 2024Article
- Multicentric short term and safety study of ineffective esophageal motility patients treated with RefluxStop device.Scientific reports · 2024Observational
- Short-term results of laparoscopic anti-reflux surgery with the RefluxStop device in patients with gastro-esophageal reflux disease and ineffective esophageal motility.Langenbeck's archives of surgery · 2024Article
- The Need for Updated Classification of Esophageal Motility Disorders Using High-resolution Impedance Manometry.Journal of neurogastroenterology and motility · 2024Article
- Chicago Classification Version 4.0 and Its Impact on Current Clinical Practice.Gastroenterology & hepatology · 2021Article
- Ineffective esophageal motility is not a contraindication to total fundoplication.Surgical endoscopy · 2021Article
- High-Resolution Manometry Diagnosis of Ineffective Esophageal Motility Is Associated with Higher Reflux Burden.Digestive diseases and sciences · 2019Article
- Ineffective Esophageal Motility Is Associated with Impaired Bolus Clearance but Does Not Correlate with Severity of Dysphagia.Digestive diseases and sciences · 2019Article
- High Resolution Impedance Manometry: A Necessity or Luxury in Esophageal Motility Disorder?The American journal of case reports · 2018Article
- A study of dysphagia symptoms and esophageal body function in children undergoing anti-reflux surgery.United European gastroenterology journal · 2018Article
- Diabetes and the Esophagus.Current treatment options in gastroenterology · 2017Review
- High-resolution esophageal manometry: interpretation in clinical practice.Current opinion in gastroenterology · 2017Review
- Esophageal motility disorders-Symptomatic and manometric spectrum in Punjab, northern India.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2017Article
- Ineffective esophageal motility and the vagus: current challenges and future prospects.Clinical and experimental gastroenterology · 2016Review
- Clinical and pH study characteristics in reflux patients with and without ineffective oesophageal motility (IEM).BMJ open gastroenterology · 2016Article
- Prosthetic rehabilitation in patient with achalasia cardia - A rare case report.Journal of International Society of Preventive & Community DentistryArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ineffective esophageal motility (IEM) is characterized by distal esophageal contraction amplitude of <30 mmHg on conventional manometry (Blonski et al. Am J Gastroenterol. 103(3):699-704, 2008), or a distal contractile integral (DCI) < 450 mmHg*s*cm on high-resolution manometry (HRM) (Kahrilas et al. Neurogastroenterol Motil. 27(2):160-74, 2015) in≥50 % of test swallows. IEM is the most common abnormality on esophageal manometry, with an estimated prevalence of 20-30 % (Tutuian and Castell Am J Gastroenterol. 99(6):1011-9, 2004; Conchillo et al. Am J Gastroenterol. 100(12):2624-32, 2005). Non-obstructive dysphagia has been considered to be frequently associated with severe esophageal peristaltic dysfunction. Defective bolus transit (DBT) on multichannel intraluminal impedance testing was found in more than half of IEM patients who presented with dysphagia (Tutuian and Castell Am J Gastroenterol. 99(6):1011-9, 2004), highlighting the functional defect of this manometric finding. Treatment of IEM has been challenging because of lack of promotility agents that have a definite effect on esophageal function.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.