Evidence map›Paper›PMID 26685306›Full record

ArticleBioinformatics (Oxford, England)2016

PaxtoolsR: pathway analysis in R using Pathway Commons.

Augustin Luna, Özgün Babur, Bülent Arman Aksoy, Emek Demir, Chris Sander

Abstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. BioPAX in 2024: Where we are and where we are heading.Computational and structural biotechnology journal · 2024
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. PyBioPAX: biological pathway exchange in Python.Journal of open source software · 2022
    Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Augustin LunaComputational Biology Center, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Özgün BaburComputational Biology Center, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Bülent Arman AksoyComputational Biology Center, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Emek DemirComputational Biology Center, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Chris SanderComputational Biology Center, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.

Funding

TR&D 3 - Network Guided Machine LearningP41GM103504 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI IDEKER, TREY · 2012 to 2024
$17.3M
Pathway Commons: Research Resource for Biological PathwaysU41HG006623 · NHGRI · SLOAN-KETTERING INST CAN RESEARCH · PI SANDER, CHRIS · 2012 to 2017
$5.7M
Chemogenomic Analysis of the NCI Therapeutic Compound DatabaseF32CA192901 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI LUNA, AUGUSTIN · 2015 to 2017
$165k
NCI NIH HHS F32 CA192901NHGRI NIH HHS U41 HG006623NIGMS NIH HHS P41 GM103504
6 · The paper itself

Abstract

purposePaxtoolsR package enables access to pathway data represented in the BioPAX format and made available through the Pathway Commons webservice for users of the R language to aid in advanced pathway analyses. Features include the extraction, merging and validation of pathway data represented in the BioPAX format. This package also provides novel pathway datasets and advanced querying features for R users through the Pathway Commons webservice allowing users to query, extract and retrieve data and integrate these data with local BioPAX datasets. AVAILABILITY AND IMPLEMENTATION: The PaxtoolsR package is compatible with versions of R 3.1.1 (and higher) on Windows, Mac OS X and Linux using Bioconductor 3.0 and is available through the Bioconductor R package repository along with source code and a tutorial vignette describing common tasks, such as data visualization and gene set enrichment analysis. Source code and documentation are at http://www.bioconductor.org/packages/paxtoolsr This plugin is free, open-source and licensed under the LGPL-3. CONTACT: paxtools@cbio.mskcc.org or lunaa@cbio.mskcc.org.

Indexed as

SoftwareComputational BiologyDocumentationProgramming Languages

Identifiers

PMID26685306
PMCPMC4824129

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.