Evidence map›Paper›PMID 26685128›Full record

ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2017

White matter changes after stroke in type 2 diabetic rats measured by diffusion magnetic resonance imaging.

Guangliang Ding, Jieli Chen, Michael Chopp, Lian Li, Tao Yan, Esmaeil Davoodi-Bojd, Qingjiang Li, Siamak Pn Davarani, Quan Jiang

Open access · bronzeAbstract read
In one paragraph

Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Guangliang DingDepartment of Neurology, Henry Ford Hospital, Detroit, MI, USA.
Jieli ChenDepartment of Neurology, Henry Ford Hospital, Detroit, MI, USA.
Michael ChoppDepartment of Neurology, Henry Ford Hospital, Detroit, MI, USA.
Lian LiDepartment of Neurology, Henry Ford Hospital, Detroit, MI, USA.
Tao YanDepartment of Neurology, Henry Ford Hospital, Detroit, MI, USA.
Esmaeil Davoodi-BojdDepartment of Neurology, Henry Ford Hospital, Detroit, MI, USA.
Qingjiang LiDepartment of Neurology, Henry Ford Hospital, Detroit, MI, USA.
Siamak Pn DavaraniDepartment of Neurology, Henry Ford Hospital, Detroit, MI, USA.
Quan JiangDepartment of Neurology, Henry Ford Hospital, Detroit, MI, USA QJIANG1@hfhs.org.
Henry Ford Hospital · USOakland University · US

Funding

Investigation of D-4F effects of neurovascular remodeling after diabetic strokeR01NS097747 · NINDS · HENRY FORD HEALTH SYSTEM · PI CUI, XU, JIANG, QUAN · 2017 to 2021
$2.2M
Neurorestorative therapy of stroke with HUCBC in type two diabetic miceR01NS083078 · NINDS · HENRY FORD HEALTH SYSTEM · PI CHEN, JIELI · 2014 to 2018
$1.6M
MSCs Induce Brain Plasticity via tPAR01AG037506 · NIA · HENRY FORD HEALTH SYSTEM · PI CHOPP, MICHAEL · 2011 to 2015
$1.5M
Imaging Cell Based Treatment of Traumatic Brain InjuryR01NS064134 · NINDS · HENRY FORD HEALTH SYSTEM · PI JIANG, QUAN · 2011 to 2014
$1.3M
MiR-126/ABCA1 mediates exosome induced neurorestorative effects after stroke in T2DM miceR01NS099030 · NINDS · HENRY FORD HEALTH SYSTEM · PI CHEN, JIELI · 2016 to 2018
$984k
Neurorestorative therapy of stroke with HUCBC in T2DM ratsR41NS080329 · NINDS · SANERON CCEL THERAPEUTICS, INC. · PI CHEN, JIELI · 2013 to 2014
$423k
NIA NIH HHS R01 AG037506NINDS NIH HHS R01 NS064134NINDS NIH HHS R01 NS083078NINDS NIH HHS R01 NS097747NINDS NIH HHS R01 NS099030NINDS NIH HHS R41 NS080329
6 · The paper itself

Abstract

Diffusion-related magnetic resonance imaging parametric maps may be employed to characterize white matter of brain. We hypothesize that entropy of diffusion anisotropy may be most effective for detecting therapeutic effects of bone marrow stromal cell treatment of ischemia in type 2 diabetes mellitus rats. Type 2 diabetes mellitus was induced in adult male Wistar rats. These rats were then subjected to 2 h of middle cerebral artery occlusion, and received bone marrow stromal cell (5 × 10

Indexed as

AnimalsAxonsBone Marrow CellsBrainDiabetes Mellitus, ExperimentalDiabetes Mellitus, Type 2Infarction, Middle Cerebral ArteryMagnetic Resonance ImagingMaleRatsRats, WistarStrokeStromal CellsWhite Matterdiabetesdiffusionmagnetic resonance imagingstrokeWhite matter

Identifiers

PMID26685128
PMCPMC5363742
OpenAlexW2413020829

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.