Evidence map›Paper›PMID 26684872›Full record

Trial reportPloS one2015

Economic Evaluation of a General Hospital Unit for Older People with Delirium and Dementia (TEAM Randomised Controlled Trial).

Lukasz Tanajewski, Matthew Franklin, Georgios Gkountouras, Vladislav Berdunov, Rowan H Harwood, Sarah E Goldberg, Lucy E Bradshaw, John R F Gladman, Rachel A Elliott

Registry-linked trialOpen access · goldAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01136148 (Evaluation of a Medical and Mental Health Unit Compared With Standard Care for Older People Whose Emergency Admission to an Acute General Hospital is Complicated by Concurrent 'Confusion'.), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
8.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01136148 nacompletednot on this map

Evaluation of a Medical and Mental Health Unit Compared With Standard Care for Older People Whose Emergency Admission to an Acute General Hospital is Complicated by Concurrent 'Confusion'.

TypeinterventionalSponsorUniversity of NottinghamRan2010 to 2012Enrolled600ConditionsDementia, Confusion, Cognitive Impairment, DeliriumArmsA medical and mental health unit
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 23 citations in OpenAlex.

  1. Cost-effectiveness of the special care unit for persons with dementia.The journal of prevention of Alzheimer's disease · 2026
    Article
  2. Article
  3. Article
  4. The financial and social costs of delirium.European geriatric medicine · 2020
    Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Lukasz TanajewskiSchool of Pharmacy, University of Nottingham, Nottingham, United Kingdom.
Matthew FranklinSchool of Pharmacy, University of Nottingham, Nottingham, United Kingdom.
Georgios GkountourasSchool of Pharmacy, University of Nottingham, Nottingham, United Kingdom.
Vladislav BerdunovSchool of Pharmacy, University of Nottingham, Nottingham, United Kingdom.
Rowan H HarwoodHealth Care of Older People, Nottingham University Hospitals NHS Trust, Queens Medical Centre, Nottingham, United Kingdom.
Sarah E GoldbergSchool of Health Sciences, University of Nottingham, Nottingham, United Kingdom.
Lucy E BradshawDivision of Rehabilitation and Ageing, University of Nottingham, Nottingham, United Kingdom.
John R F GladmanDivision of Rehabilitation and Ageing, University of Nottingham, Nottingham, United Kingdom.
Rachel A ElliottSchool of Pharmacy, University of Nottingham, Nottingham, United Kingdom.
University of Nottingham · GBQueen's Medical Centre · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOne in three hospital acute medical admissions is of an older person with cognitive impairment. Their outcomes are poor and the quality of their care in hospital has been criticised. A specialist unit to care for older people with delirium and dementia (the Medical and Mental Health Unit, MMHU) was developed and then tested in a randomised controlled trial where it delivered significantly higher quality of, and satisfaction with, care, but no significant benefits in terms of health status outcomes at three months.

objectiveTo examine the cost-effectiveness of the MMHU for older people with delirium and dementia in general hospitals, compared with standard care.

methodsSix hundred participants aged over 65 admitted for acute medical care, identified on admission as cognitively impaired, were randomised to the MMHU or to standard care on acute geriatric or general medical wards. Cost per quality adjusted life year (QALY) gained, at 3-month follow-up, was assessed in trial-based economic evaluation (599/600 participants, intervention: 309). Multiple imputation and complete-case sample analyses were employed to deal with missing QALY data (55%).

resultsThe total adjusted health and social care costs, including direct costs of the intervention, at 3 months was £7714 and £7862 for MMHU and standard care groups, respectively (difference -£149 (95% confidence interval [CI]: -298, 4)). The difference in QALYs gained was 0.001 (95% CI: -0.006, 0.008). The probability that the intervention was dominant was 58%, and the probability that it was cost-saving with QALY loss was 39%. At £20,000/QALY threshold, the probability of cost-effectiveness was 94%, falling to 59% when cost-saving QALY loss cases were excluded.

conclusionsThe MMHU was strongly cost-effective using usual criteria, although considerably less so when the less acceptable situation with QALY loss and cost savings were excluded. Nevertheless, this model of care is worthy of further evaluation.

trial registrationClinicalTrials.gov NCT01136148.

Indexed as

AgedAged, 80 and overCost-Benefit AnalysisDeliriumDementiaHealth Services for the AgedHospitals, GeneralHumansQuality-Adjusted Life Years

Identifiers

PMID26684872
PMCPMC4687694
OpenAlexW2206212608

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.