Evidence map›Paper›PMID 26684748›Full record

ArticlePloS one2015

Fasting Glucose Levels Correlate with Disease Severity of Guillain-Barré Syndrome.

Ying Wang, Guihong Li, Siyu Yang, Xiaoyi Gu, Xinyu Li, Mingyang Liu, Xiujuan Wu, Yun Guan, Rayomand Press, Jie Zhu and 1 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Trial
  2. Guillain-Barré syndrome.BJA education · 2025
    Review
  3. Article
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Ying WangDepartment of Neurology, the First Hospital of Jilin University, Changchun, China.
Guihong LiNorman Bethune Health Science Center, Jilin University, Changchun, China.
Siyu YangNorman Bethune Health Science Center, Jilin University, Changchun, China.
Xiaoyi GuNorman Bethune Health Science Center, Jilin University, Changchun, China.
Xinyu LiNorman Bethune Health Science Center, Jilin University, Changchun, China.
Mingyang LiuNorman Bethune Health Science Center, Jilin University, Changchun, China.
Xiujuan WuDepartment of Neurology, the First Hospital of Jilin University, Changchun, China.
Yun GuanShanghai Medical College, Fudan University, Shanghai, China.
Rayomand PressDivision of Neurology, Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden.
Jie ZhuDepartment of Neurology, the First Hospital of Jilin University, Changchun, China.
Hong-Liang ZhangDepartment of Neurology, the First Hospital of Jilin University, Changchun, China.
First Bethune Hospital of Jilin University · CNFirst Hospital of Jilin University · CNJilin University · CNKarolinska Institutet · SEShanghai Medical College of Fudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveA potential association between diabetes and Guillain-Barré syndrome (GBS) has been indicated by a few case studies. We retrospectively analyzed the clinical features of a large cohort of GBS patients to explore the relationship between the level of fasting plasma glucose (FPG) obtained in the acute phase at admission and the severity of GBS.

methodsThree hundred and four GBS patients were divided into two groups, one with normal FPG and the other with high FPG levels according to the international standards of FPG.

resultsThe GBS disability scale score was positively, the Medical Research Council (MRC) sum score was negatively correlated to the level of FPG, but not to blood HBA1c or CSF glucose concentrations. A relatively higher FPG level was observed in older and younger GBS patients, and more often in those with cranial nerve involvement, autonomic deficit, dyspnea and ventilator dependence than in patients without these clinical characteristics. Importantly, higher levels of FPG at admission were associated with poorer short-term prognosis measured by the MRC sum score and the GBS disability scale at discharge.

conclusionsOur data demonstrates that FPG in the acute phase of GBS correlates with the severity of GBS and may predict the short-term prognosis of GBS.

Indexed as

AdultBlood GlucoseFemaleGuillain-Barre SyndromeHumansMaleMiddle AgedPrognosisRisk FactorsSeverity of Illness IndexYoung AdultBlood Glucose

Identifiers

PMID26684748
PMCPMC4684199
OpenAlexW2209953568

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.