Evidence map›Paper›PMID 26684623›Full record

ArticleInternational journal of immunopathology and pharmacology2016

Yiqi Wenyang Fang ameliorates allergic rhinitis through inhibiting inflammatory response and promoting the expression of Foxp3.

Jun Shi, Yu Liu, Shihai Yan, Daonan Yan

Abstract read
In one paragraph

Article in International journal of immunopathology and pharmacology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Difference between CD25Brazilian journal of otorhinolaryngology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jun ShiDepartment of Otolaryngology, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing City, Jiangsu Province, PR China.
Yu LiuDepartment of Otolaryngology, the First Clinical Medical College, Nanjing University of Chinese Medicine, Nanjing City, Jiangsu Province, PR China.
Shihai YanDepartment of Otolaryngology, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing City, Jiangsu Province, PR China.
Daonan YanDepartment of Otolaryngology, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing City, Jiangsu Province, PR China daonanyann@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Allergic rhinitis (AR) is an inflammatory disease with a hypersensitivity response to environmental stimulus. The aim of this study was to evaluate the effect of Yiqi Wenyang Fang (YWF) on AR and investigate the underlying mechanism. A total of 48 female Sprague-Dawley rats were randomly divided into six groups (normal control, model control, YWF at low dose, YWF at median dose, YWF at high dose, and loratadine). Rats were injected with antigen for sensitization. Then, rats in the YWF groups were treated with different dose of YWF for 28 days. Loratadine was used as a positive control. Number of sneezes, degree of runny nose, nasal rubbing movements, and tissue damage were scored. The protein and mRNA expression of Foxp3 were determined by western blot and real time-PCR analysis, respectively. Flow cytometry was used to detect the number of CD4

Indexed as

AnimalsCD4-Positive T-LymphocytesDrugs, Chinese HerbalFemaleForkhead Transcription FactorsInflammationInterleukin-10Interleukin-13Interleukin-2 Receptor alpha SubunitInterleukin-4Medicine, Chinese TraditionalNasal MucosaRatsRats, Sprague-DawleyRhinitis, AllergicT-Lymphocytes, RegulatoryDrugs, Chinese HerbalForkhead Transcription FactorsFoxp3 protein, ratInterleukin-10Interleukin-13Interleukin-2 Receptor alpha SubunitInterleukin-4allergic rhinitiscytokinesFoxp3inflammatory responseYiqi Wenyang Fang

Identifiers

PMID26684623
PMCPMC5806833

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.