ArticleJournal of pediatric rehabilitation medicine2015
Neural substrates of inhibitory and emotional processing in adolescents with traumatic brain injury.
Article in Journal of pediatric rehabilitation medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 11 citations in OpenAlex.
- Sexual Dimorphisms in Neurodevelopment May Affect TBI Recovery in Pediatric Patients.Biomedicines · 2025Review
- Neuroimaging Correlates of Functional Outcome Following Pediatric TBI.Advances in neurobiology · 2024Review
- Neural response to monetary incentives in acquired adolescent depression after mild traumatic brain injury: Stage 2 Registered Report.Brain communications · 2024Article
- Cognitive and cortical network alterations in pediatric temporal lobe space-occupying lesions: an fMRI study.Frontiers in human neuroscience · 2024Article
- Abnormal structural and functional network topological properties associated with left prefrontal, parietal, and occipital cortices significantly predict childhood TBI-related attention deficits: A semi-supervised deep learning study.Frontiers in neuroscience · 2023Article
- Abnormal Functional Network Topology and Its Dynamics during Sustained Attention Processing Significantly Implicate Post-TBI Attention Deficits in Children.Brain sciences · 2021Article
- Neuroimaging of the Injured Pediatric Brain: Methods and New Lessons.The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry · 2018Review
- Traumatic Brain Injury, Sleep Disorders, and Psychiatric Disorders: An Underrecognized Relationship.Medical sciences (Basel, Switzerland) · 2018Review
- Response Inhibition Deficits and Altered Motor Network Connectivity in the Chronic Phase of Pediatric Traumatic Brain Injury.Journal of neurotrauma · 2017Article
- Diffusion MRI in pediatric brain injury.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2017Review
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
purposeDisturbances of emotional regulation and social difficulties are common in children and adolescents with traumatic brain injury (TBI). Recent research suggests that developments within ``socio-emotional'' brain systems during early adolescence and more protracted development of "cognitive control'' systems have implications for emotional and behavioral regulation during adolescence. However, few functional neuroimaging studies have directly examined the interaction of these neuropsychological processes in adolescents with TBI. The current study examined how affective processing might modulate inhibitory processing in an Emotional Go/NoGo paradigm.
methodThe study uses a cross-sectional, age, gender, and maternal education matched design.A response inhibition paradigm (i.e., the Go/NoGo task with emotional faces) was used to examine emotional-cognition interaction in 11 adolescents with complicated mild to moderate TBI, at least 12 months post injury, and 14 typically-developing (TD) adolescents using functional magnetic resonance imaging (fMRI). Participants saw adult facial expressions of emotions (happy, sad, fearful, and angry) and were instructed to respond (``go'') on all expressions other than angry (``no-go'').
resultsPreliminary results (p= 0.001 uncorrected, cluster size = 50) showed higher levels of inhibition-related activation in TD adolescents than in adolescents with TBI in several brain regions including anterior cingulate and motor/premotor regions.
conclusionThese results suggest that TBI in adolescence might alter brain activation patterns and interrupt the development of brain networks governing emotion-cognition interactions.
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Registered trials
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