Evidence map›Paper›PMID 26683926›Full record

Observational studyMedicine2015

Serum Gamma-Glutamyltransferase Levels are Associated With Concomitant Cardiovascular Risk Factors in Korean Hypertensive Patients: A Nationwide Population-Based Study.

Sangsu Lee, Do Hoon Kim, Hyo Yun Nam, Yong-Kyun Roh, Sang-Yhun Ju, Yeo-Joon Yoon, Ga-Eun Nam, Jun-Seok Choi, Jong-Eun Lee, Jung-Eun Sang and 2 more

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 2 countries.

Sangsu LeeFrom the Department of Family Medicine, Korea University, College of Medicine, Seoul (SL, DHK, HYN, Y-JY, G-EN, J-SC, J-EL, J-ES); Department of Family Medicine, Hallym University, College of Medicine, Chunchon (Y-KR); Department of Family Medicine, Catholic University, College of Medicine (S-YJ); Department of Biostatistics, Catholic University, College of Medicine, Seoul, Republic of Korea (KDH, Y-GP).
Do Hoon Kim
Hyo Yun Nam
Yong-Kyun Roh
Sang-Yhun Ju
Yeo-Joon Yoon
Ga-Eun Nam
Jun-Seok Choi
Jong-Eun Lee
Jung-Eun Sang
Kyungdo Han
Yong-Gyu Park
Yarmouk Private University · SY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous studies suggested that serum gamma-glutamyltransferase (GGT) levels were associated with the prevalence of cardiovascular disease (CVD) risk factors including hypertension, diabetes mellitus (DM), and metabolic syndrome (MetS) in the general population. We aimed to investigate the relationship between serum GGT levels and CVD risk factors in Korean hypertensive patients. This cross-sectional study was based on data from the Korea National Health and Nutrition Examination Survey (KNHANES) 2011 to 2012. The analysis included 1541 hypertensive participants. Study participants were divided into groups according to tertiles of serum GGT with cutoff points of 20 and 35 U/L. Serum GGT levels were positively associated with the components of MetS (P value < 0.05, except for systolic blood pressure and high-density lipoprotein cholesterol). After adjusting for possible confounders, serum GGT levels were associated with an increased risk of MetS, high waist circumference, high triglyceride level, fasting plasma glucose, DM, and the urinary albumin-to-creatinine ratio (P = 0.001). In hypertensive patients, serum GGT levels are positively associated with major cardiovascular risk factors such as MetS, DM, and urinary albumin excretion.

Indexed as

AdultAgedBlood GlucoseBlood PressureBody Mass IndexBody Weights and MeasuresCardiovascular DiseasesCreatinineCross-Sectional StudiesDiabetes MellitusDyslipidemiasFemalegamma-GlutamyltransferaseHumansHypertensionMaleBlood GlucoseCreatininegamma-Glutamyltransferase

Identifiers

PMID26683926
PMCPMC5058898
OpenAlexW2257806952

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.