Evidence map›Paper›PMID 26683287›Full record

ArticleScandinavian journal of primary health care2015

Appropriateness of antibiotic prescribing for upper respiratory tract infections in general practice: Comparison between Denmark and Iceland.

Nanna Rún Sigurðardóttir, Anni Brit Sternhagen Nielsen, Anders Munck, Lars Bjerrum

Abstract readComparative Study
In one paragraph

Article in Scandinavian journal of primary health care, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Probiotics for preventing acute upper respiratory tract infections.The Cochrane database of systematic reviews · 2022
    Pooled it
  3. Antibiotics for acute rhinosinusitis in adults.The Cochrane database of systematic reviews · 2018
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nanna Rún Sigurðardóttira Section and Research Unit for General Practice, Department of Public Health , University of Copenhagen , Copenhagen , Denmark ;
Anni Brit Sternhagen Nielsena Section and Research Unit for General Practice, Department of Public Health , University of Copenhagen , Copenhagen , Denmark ;
Anders Munckb Audit Project Odense, Research Unit of General Practice , University of Southern Denmark , Odense , Denmark.
Lars Bjerruma Section and Research Unit for General Practice, Department of Public Health , University of Copenhagen , Copenhagen , Denmark ;

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare the appropriateness of antibiotic prescribing for upper respiratory tract infections (URTIs) in two countries with different prevalence of antimicrobial resistance: Denmark and Iceland.

designA cross-sectional study. SETTINGS AND SUBJECTS: General practitioners (GPs) in Denmark (n = 78) and Iceland (n = 21) registered all patients with URTI according to the Audit Project Odense (APO) method during a three-week period in the winter months of 2008 and 2009.

main outcome measuresAppropriateness of antibiotic prescribing in patients with URTI in Denmark and Iceland.

resultsA total of 1428 patients were registered (Denmark: n = 1208; Iceland: n = 220). A majority of patients in both countries were prescribed antibiotics, and only a minority of the prescriptions could be classified as appropriate prescribing. In general, Icelandic GPs more often prescribed antibiotics (Iceland = 75.8% vs. Denmark = 59.3%), but Danish GPs had a higher percentage of inappropriate antibiotic prescribing for sinusitis, and Icelandic GPs for pharyngotonsillitis. No differences were found for acute otitis media (AOM). The different antibiotic prescribing patterns between Denmark and Iceland could not fully be explained by different symptoms and signs among patients.

conclusionIcelandic GPs have a higher antibiotic prescribing rate compared with Danish GPs, but the percentage of inappropriate antibiotic prescribing is highest in Denmark for sinusitis, and in Iceland for pharyngotonsillitis. Key points Within the Nordic countries there are marked differences in antimicrobial resistance and antibiotic use. Iceland differs from Denmark by a higher antibiotic prescribing rate and a higher prevalence of antimicrobial resistance. The majority of antibiotics are prescribed in primary care and most often for upper respiratory infections (URTIs). Only a minor amount of antibiotic prescriptions for URTIs can be classified as appropriate; inappropriate antibiotic prescribing is higher in Denmark than in Iceland for sinusitis and the opposite for pharyngotonsillitis. The different antibiotic prescribing patterns between Denmark and Iceland cannot be fully explained by different clinical criteria among patients.

Indexed as

AdolescentAdultAgedAnti-Bacterial AgentsBacterial InfectionsChildClinical AuditCross-Sectional StudiesDenmarkDrug Resistance, BacterialFamily PracticeFemaleHumansIcelandInappropriate PrescribingMaleAnti-Bacterial AgentsAntibioticsDenmarkdiagnostic criteriageneral practiceupper respiratory tract infection

Identifiers

PMID26683287
PMCPMC4750736

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.