ArticleClinical research in cardiology : official journal of the German Cardiac Society2016
Deep sedation versus general anesthesia in percutaneous edge-to-edge mitral valve reconstruction using the MitraClip system.
Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- Deep sedation versus general anaesthesia for transcatheter mitral valve repair: an individual patient data meta-analysis of observational studies.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2021Pooled it
- Comparing sedation vs. general anaesthesia in transoesophageal echocardiography-guided percutaneous transcatheter mitral valve repair: a meta-analysis.European heart journal. Cardiovascular Imaging · 2020Pooled it
- Effects of adding low-dose esketamine to sufentanil and propofol sedation during cervical conization: a single-centre, randomized controlled trial.BMC anesthesiology · 2024Trial
- Streamlining postprocedural care after transcatheter edge-to-edge repair.BMC cardiovascular disorders · 2026Article
- Re-do MitraClip in patients with functional mitral valve regurgitation and advanced heart failure.ESC heart failure · 2021Article
- Two year outcome in nonagenarians undergoing percutaneous mitral valve repair.ESC heart failure · 2021Article
- Impact of conscious sedation and general anesthesia on periprocedural outcomes in Watchman left atrial appendage closure.Cardiology journal · 2021Article
- One more option in heart failure: correction of mitral regurgitation with MitraClipInternal and emergency medicine · 2019Review
- [Nonoperating room anesthesia].Der Anaesthesist · 2019Review
- Invasive hemodynamics and cardiac biomarkers to predict outcomes after percutaneous edge-to-edge mitral valve repair in patients with severe heart failure.Clinical research in cardiology : official journal of the German Cardiac Society · 2019Article
- Atrioventricular valve disease: challenges and achievements in percutaneous treatment.Clinical research in cardiology : official journal of the German Cardiac Society · 2018Review
- High body mass index is a risk factor for difficult deep sedation in percutaneous mitral valve repair.PloS one · 2018Article
- Comparison of Deep Sedation With General Anesthesia in Patients Undergoing Percutaneous Mitral Valve Repair.Journal of the American Heart Association · 2017Article
- Impact of cardiac comorbidities on early and 1-year outcome after percutaneous mitral valve interventions: data from the German transcatheter mitral valve interventions (TRAMI) registry.Clinical research in cardiology : official journal of the German Cardiac Society · 2017Article
- Comment to: De Waha S, Seeburger J et al. (2016): Deep sedation versus general anaesthesia in percutaneous edge-to edge mitral valve reconstruction using the MitraClip system. Clin Res Cardiol 105(6):535-43.Clinical research in cardiology : official journal of the German Cardiac Society · 2017Article
- Response to Prof. Dr. med. Gunther Wiesner, Prof. Dr. med. Peter Tassani-Prell, and Dr. Patrick Mayr : Deep sedation versus general anaesthesia in percutaneous edge-to-edge mitral valve reconstruction using the MitraClip system.Clinical research in cardiology : official journal of the German Cardiac Society · 2017Article
- Noninvasive ventilation during left atrial appendage closure under sedation: Preliminary experience with the Janus Mask.Annals of cardiac anaesthesiaArticle
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Authors and funding
14 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPercutaneous edge-to-edge mitral valve reconstruction (PMVR) has emerged as a treatment option in patients with severe mitral regurgitation not considered suitable candidates for surgery. The majority of PMVR procedures are performed under general anesthesia (GA), although deep sedation (DS) appears to be an attractive alternative. We thus sought to assess the impact on intensive care unit (ICU) length of stay, efficacy, and safety of DS in comparison to GA in patients undergoing PMVR using the MitraClip(®) system.
methodsSixty consecutive patients underwent PMVR procedures at two centers. The first 30 patients were treated by GA followed by 30 patients undergoing DS under different settings. The primary clinical endpoint was ICU length of stay. The primary efficacy endpoint included procedural success and procedural duration. The safety endpoint was defined as a composite of death, stroke, cardiogenic shock, moderate and severe bleeding as well as pneumonia.
resultsThe ICU length of stay was significantly shorter in the DS group in comparison to GA patients (p = 0.001). The hospital length of stay did not differ following DS in comparison to GA (p = 0.96). Procedural success was high in both groups (100 versus 96.7 %, p = 0.34) at similar procedural duration time (p = 0.60). No difference between GA and DS was observed with respect to the occurrence of the combined safety endpoint (p = 0.47).
conclusionsIn comparison to GA, DS reduces the ICU length of stay in PMVR without negative effects on safety and efficacy. Prospective randomized trials are needed to confirm these findings.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.