ArticleExperimental physiology2016
Increases in core temperature counterbalance effects of haemoconcentration on blood viscosity during prolonged exercise in the heat.
Article in Experimental physiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Assessment of blood fluidity and the development of the microchannel method for preventive medicine and disease activity evaluation.Fujita medical journal · 2026Article
- A Microfluidic Method for Simultaneous Assessment of Blood Viscosity and Red Blood Cell Aggregation During Continuous Syringe Delivery.Sensors (Basel, Switzerland) · 2026Article
- The Impact of Sleep on Haematological Parameters in Firefighters.Clocks & sleep · 2024Article
- Hormonal Control of Blood Viscosity.Cureus · 2024Review
- Effects of supplementing processed velvet beans (Mucuna pruriens L. DC. var. utilis) on nutrients intakes, growth performance, and blood profile in goats.Tropical animal health and production · 2023Article
- Review
- Intravascularly infused extracellular matrix as a biomaterial for targeting and treating inflamed tissues.Nature biomedical engineering · 2023Article
- Observational
- Effects of electrolyzed hydrogen water ingestion during endurance exercise in a heated environment on body fluid balance and exercise performance.Temperature (Austin, Tex.) · 2020Article
- Blood Rheology: Key Parameters, Impact on Blood Flow, Role in Sickle Cell Disease and Effects of Exercise.Frontiers in physiology · 2019Review
- Rat red blood cell storage lesions in various additive solutions.Clinical hemorheology and microcirculation · 2017Article
- Hyperthermia during exercise - a double-edged sword.Temperature (Austin, Tex.) · 2016Article
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Authors and funding
5 authors.
Funding
Abstract
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findingsWhat is the central question of this study? The purpose of the present study was to determine the effects of exercise-induced haemoconcentration and hyperthermia on blood viscosity. What is the main finding and its importance? Exercise-induced haemoconcentration, increased plasma viscosity and increased blood aggregation, all of which increased blood viscosity, were counterbalanced by increased red blood cell (RBC) deformability (e.g. RBC membrane shear elastic modulus and elongation index) caused by the hyperthermia. Thus, blood viscosity remained unchanged following prolonged moderate-intensity exercise in the heat. Previous studies have reported that blood viscosity is significantly increased following exercise. However, these studies measured both pre- and postexercise blood viscosity at 37 °C even though core and blood temperatures would be expected to have increased during the exercise. Consequently, the effect of exercise-induced hyperthermia on mitigating change in blood viscosity may have been missed. The purpose of this study was to isolate the effects of exercise-induced haemoconcentration and hyperthermia and to determine their combined effects on blood viscosity. Nine subjects performed 2 h of moderate-intensity exercise in the heat (37 °C, 40% relative humidity), which resulted in significant increases from pre-exercise values for rectal temperature (from 37.11 ± 0.35 to 38.76 ± 0.13 °C), haemoconcentration (haematocrit increased from 43.6 ± 3.6 to 45.6 ± 3.5%) and dehydration (change in body weight = -3.6 ± 0.7%). Exercise-induced haemoconcentration significantly (P < 0.05) increased blood viscosity by 9% (from 3.97 to 4.33 cP at 300 s(-1)), whereas exercise-induced hyperthermia significantly decreased blood viscosity by 7% (from 3.97 to 3.69 cP at 300 s(-1)). When both factors were considered together, there was no overall change in blood viscosity (from 3.97 to 4.03 cP at 300 s(-1)). The effects of exercise-induced haemoconcentration, increased plasma viscosity and increased red blood cell aggregation, all of which increased blood viscosity, were counterbalanced by increased red blood cell deformability (e.g. red blood cell membrane shear elastic modulus and elongation index) caused by the hyperthermia. Thus, blood viscosity remained unchanged following prolonged moderate-intensity exercise in the heat.
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