Evidence map›Paper›PMID 26682499›Full record

ArticleTrends in biochemical sciences2016

The Biochemical Evolution of Protein Complexes.

Todd M Greco, Ileana M Cristea

Abstract readComment
In one paragraph

Article in Trends in biochemical sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Todd M GrecoDepartment of Molecular Biology, 210 Lewis Thomas Laboratory, Princeton University, Princeton, NJ 08544, USA.
Ileana M CristeaDepartment of Molecular Biology, 210 Lewis Thomas Laboratory, Princeton University, Princeton, NJ 08544, USA. Electronic address: icristea@princeton.edu.
Princeton University · US

Funding

Mechanisms mediating immune response upon sensing of nuclear viral DNAR01GM114141 · NIGMS · PRINCETON UNIVERSITY · PI CRISTEA, ILEANA M. · 2015 to 2023
$2.6M
Functional investigation of the TBX20 cardiac interactomeR01HL127640 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CONLON, FRANK LEO, CRISTEA, ILEANA M. · 2015 to 2018
$2.5M
NHLBI NIH HHS HL127640NHLBI NIH HHS R01 HL127640NIGMS NIH HHS GM114141NIGMS NIH HHS R01 GM114141
6 · The paper itself

Abstract

Over the past decade, it became evident that proteins perform critical functions as components of specialized macromolecular complexes. Here, we discuss a recent study by Wan and colleagues, which highlights the significance of protein complexes by studying their conservation in organisms separated by up to a billion years of evolution.

Indexed as

Evolution, MolecularProtein Interaction MapsAnimalsHumansMultiprotein ComplexesMultiprotein Complexesevolutioninteractomemacromolecular complexmass spectrometryProtein interactionsprotein-protein interaction

Identifiers

PMID26682499
PMCPMC4706493
OpenAlexW2191571902

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.