ArticleJournal of cardiovascular development and disease2015
Genetic Regulation of Sinoatrial Node Development and Pacemaker Program in the Venous Pole.
Article in Journal of cardiovascular development and disease, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 26 citations in OpenAlex.
- The Neglected Internodal Tract-A Cardiac Conduction System Structure Homologous to the Development and Regulation of the Sinoatrial Node.Reviews in cardiovascular medicine · 2025Review
- Molecular Regulation of Cardiac Conduction System Development.Current cardiology reports · 2024Review
- Segregation of morphogenetic regulatory function of Shox2 from its cell fate guardian role in sinoatrial node development.Communications biology · 2024Article
- Local tissue mechanics control cardiac pacemaker cell embryonic patterning.Life science alliance · 2023Article
- Decoding the PITX2-controlled genetic network in atrial fibrillation.JCI insight · 2022Article
- Altered microRNA and mRNA profiles during heart failure in the human sinoatrial node.Scientific reports · 2021Article
- Assembly of the Cardiac Pacemaking Complex: Electrogenic Principles of Sinoatrial Node Morphogenesis.Journal of cardiovascular development and disease · 2021Review
- PDGFRα-Signaling Is Dispensable for the Development of the Sinoatrial Node After Its Fate Commitment.Frontiers in cell and developmental biology · 2021Article
- ATAC-Seq Reveals anCirculation research · 2020Article
- Association of Dysplastic Coronoid Process with Long-Face Morphology.Journal of dental research · 2020Article
- Comparative study of hyperpolarization-activated currents in pulmonary vein cardiomyocytes isolated from rat, guinea pig, and rabbit.The journal of physiological sciences : JPS · 2020Article
- Differences in Expression of Genes Involved in Bone Development and Morphogenesis in the Walls of Internal Thoracic Artery and Saphenous Vein Conduits May Provide Markers Useful for Evaluation Graft Patency.International journal of molecular sciences · 2019Article
- Article
- Functional Characterization of Rare Variants in theFrontiers in genetics · 2019Article
- Interplay between cardiac transcription factors and non-coding RNAs in predisposing to atrial fibrillation.Journal of molecular medicine (Berlin, Germany) · 2018Review
- AInternational journal of medical sciences · 2018Article
- Development of the cardiac pacemaker.Cellular and molecular life sciences : CMLS · 2017Review
- A unique stylopod patterning mechanism by Shox2-controlled osteogenesis.Development (Cambridge, England) · 2016Article
- Coding and non-coding variants in the SHOX2 gene in patients with early-onset atrial fibrillation.Basic research in cardiology · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
The definitive sinoatrial node (SAN), the primary pacemaker of the mammalian heart, develops from part of pro-pacemaking embryonic venous pole that expresses both Hcn4 and the transcriptional factor Shox2. It is noted that ectopic pacemaking activities originated from the myocardial sleeves of the pulmonary vein and systemic venous return, both derived from the
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.