ArticleBritish microbiology research journal2015
Proteolytic Activities Expressed by Gastrointestinal Pathogens
Article in British microbiology research journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed, 10 citations in OpenAlex.
- Comparative seropositivity ofSAGE open medicine · 2024Article
- Inhibition of Collagenase Q1 ofAdvanced therapeutics · 2022Article
- The proteolytic activity of Listeria monocytogenes HtrA.BMC microbiology · 2019Article
- A Clinicopathological Analysis of Six Autopsy Cases of Sudden Unexpected Death due to Infectious Aortitis in Patients with Aortic Tears.Internal medicine (Tokyo, Japan) · 2018Article
- Effect of ModifiedEvidence-based complementary and alternative medicine : eCAM · 2017Article
- Cloning, Purification and Characterization of the Collagenase ColA Expressed by Bacillus cereus ATCC 14579.PloS one · 2016Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
aimsBacterial proteases are implicated in protein quality control, biofilm formation or might have a direct function in pathogenesis by processing virulence factors or cleaving host factors. In recent years, knowledge of proteases expressed by Gram-negative pathogens remarkably increased. However, investigation of proteases from Gram-positive bacteria is rather rare, but required for the analysis of pathogenesis-relevant proteases. In this study, we extracted and detected proteases from the gastrointestinal pathogens METHODOLOGY: Bacteria were grown to logarithmic or stationary phases, harvested and extracted by sonication and French press. For the detection of active proteases, zymography analyses were performed using casein and gelatin as substrates to monitor caseinolytic and gelatinolytic activities.
resultsWe observed different active proteases with different intensities in bacteria grown to logarithmic or stationary phases. Strong activities as gelatinases were detected in
conclusionIn summary, the data clearly indicated proteases that are differentially regulated in the Gram-positive pathogens
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Registered trials
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