Evidence map›Paper›PMID 26682061›Full record

ArticleCell death discovery

Current questions and possible controversies in autophagy.

L M Lindqvist, A K Simon, E H Baehrecke

Open access · goldAbstract read
In one paragraph

Article in Cell death discovery. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 62 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. An Overview of Autophagy in Hematopoietic Stem Cell Transplantation.Frontiers in bioengineering and biotechnology · 2022
    Review
  12. Review
  13. Article
  14. Autophagic Cell Death During Development - Ancient and Mysterious.Frontiers in cell and developmental biology · 2021
    Review
  15. Article
  16. Article
  17. Rab GTPases in Osteoclastic Bone Resorption and Autophagy.International journal of molecular sciences · 2020
    Review
  18. Article
  19. Molecular mechanism ofOncology letters · 2019
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 3 countries.

L M LindqvistCell Signalling and Cell Death Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia ; Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia.
A K SimonTranslational Immunology Lab, BRC-NIHR, John Radcliffe Hospital, Experimental Medicine, Nuffield Department of Medicine, Oxford, UK ; MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, Oxford, UK.
E H BaehreckeDepartment of Molecular, Cell and Cancer Biology, University of Massachusetts Medical School, Worcester, MA, USA.
MRC Human Immunology Unit · GBUniversity of Massachusetts Chan Medical School · USWalter and Eliza Hall Institute of Medical Research · AU

Funding

Genetic Regulation of Autophagic Cell DeathR01GM079431 · NIGMS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI BAEHRECKE, ERIC H · 2007 to 2019
$4.4M
Interplay between the Endocrine and Innate Systems of DrosphilaR01AI099708 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI BAEHRECKE, ERIC H, SILVERMAN, NEAL · 2012 to 2023
$4.2M
Function of Atg6 and autophagy in growth controlR01CA159314 · NCI · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI BAEHRECKE, ERIC H · 2011 to 2015
$1.7M
Characterization of a novel autophagy pathwayR01GM111658 · NIGMS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI BAEHRECKE, ERIC H · 2015 to 2018
$1.3M
NCI NIH HHS R01 CA159314NIAID NIH HHS R01 AI099708NIGMS NIH HHS R01 GM079431NIGMS NIH HHS R01 GM111658Wellcome Trust 103830
6 · The paper itself

Abstract

Interest in autophagy has exploded over the last decade, with publications highlighting crosstalk with several other cellular processes including secretion, endocytosis, and cell suicide pathways including apoptosis. Autophagy proteins have also been implicated in other cellular processes independently of their roles in autophagy, creating complexities in the interpretation of autophagy (

Identifiers

PMID26682061
PMCPMC4679147
OpenAlexW2282401479

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.