Evidence map›Paper›PMID 26681191›Full record

Trial reportBMC oral health2015

Comparison of the caries-protective effect of fluoride varnish with treatment as usual in nursery school attendees receiving preventive oral health support through the Childsmile oral health improvement programme - the Protecting Teeth@3 Study: a randomised controlled trial.

William Wright, Stephen Turner, Yulia Anopa, Emma McIntosh, Olivia Wu, David I Conway, Lorna M D Macpherson, Alex D McMahon

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC oral health, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01674933 (Comparison Of The Caries-Protective Effect Of Fluoride Varnish), which is not on this map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01674933 phase4completednot on this map

Comparison Of The Caries-Protective Effect Of Fluoride Varnish (Duraphat®) With Treatment As Usual In Nursery School Attendees Receiving Preventive Oral Health Support Through The Childsmile Oral Health Improvement Programme: An RCT

TypeinterventionalSponsorUniversity of GlasgowRan2012 to 2017Enrolled1,610ConditionsDental CariesArmsDuraphat® Fluoride Varnish, treatment as usual
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Fluoride varnishes for preventing dental caries in children and adolescents.The Cochrane database of systematic reviews · 2013
    Pooled it
  2. Trial
  3. Article
  4. Does the Registered Dentists' Program Alleviate the Socioeconomic Gap in the Use of Dental Sealants?International journal of environmental research and public health · 2020
    Article
  5. A Markov cost-effective analysis of biannual fluoride varnish for preventing dental caries in permanent teeth over a 70-year time horizon.Health promotion journal of Australia : official journal of Australian Association of Health Promotion Professionals · 2020
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

William WrightCommunity Oral Health, University of Glasgow Dental School, 378 Sauchiehall Street, Glasgow, G2 3JZ, Scotland, UK. william.wright@glasgow.ac.uk.
Stephen TurnerCommunity Oral Health, University of Glasgow Dental School, 378 Sauchiehall Street, Glasgow, G2 3JZ, Scotland, UK. s.turner@dundee.ac.uk.
Yulia AnopaCommunity Oral Health, University of Glasgow Dental School, 378 Sauchiehall Street, Glasgow, G2 3JZ, Scotland, UK. yulia.Anopa@glagow.ac.uk.
Emma McIntoshHealth Economic and Health Technology Assessment, Institute of Health & Wellbeing, University of Glasgow, 1 Lilybank Gardens, Glasgow, G12 8RZ, Scotland, UK. emma.mcintosh@glasgow.ac.uk.
Olivia WuHealth Economic and Health Technology Assessment, Institute of Health & Wellbeing, University of Glasgow, 1 Lilybank Gardens, Glasgow, G12 8RZ, Scotland, UK. olivia.wu@glasgow.ac.uk.
David I ConwayCommunity Oral Health, University of Glasgow Dental School, 378 Sauchiehall Street, Glasgow, G2 3JZ, Scotland, UK. david.conway@glasgow.ac.uk.
Lorna M D MacphersonCommunity Oral Health, University of Glasgow Dental School, 378 Sauchiehall Street, Glasgow, G2 3JZ, Scotland, UK. lorna.macpherson@glasgow.ac.uk.
Alex D McMahonCommunity Oral Health, University of Glasgow Dental School, 378 Sauchiehall Street, Glasgow, G2 3JZ, Scotland, UK. Alex.McMahon@glasgow.ac.uk.
University of Glasgow · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Scottish Government set out its policy on addressing the poor oral health of Scottish children in 2005. This led to the establishment of Childsmile, a national programme designed to improve the oral health of children in Scotland. One element of the programme promotes daily tooth brushing in all nurseries in Scotland (Childsmile Core). A second targeted component (Childsmile Nursery) offers twice-yearly application of fluoride varnish to children attending nurseries in deprived areas. Studies suggest that fluoride varnish application can reduce caries in both adult and child populations. This trial aims to explore the effectiveness and cost-effectiveness of additional preventive value fluoride varnish application compared to Childsmile Core. METHODS/

designThe Protecting Teeth@3 Study is an ongoing 2 year parallel group randomised treatment as usual controlled trial. Three-year-old children attending the ante pre-school year are randomised (1:1) to the intervention arm (fluoride varnish & treatment as usual) or the control arm (treatment as usual). Children in the intervention arm will have Duraphat® fluoride varnish painted on the primary tooth surfaces and will continue to receive treatment as usual: the core Childsmile Nursery intervention. Children in the treatment as usual arm will receive the same series of contacts, without the application of varnish and will also continue with the Childsmile Core intervention. Interventions are undertaken by Childsmile trained extended duty dental nurses at six-monthly intervals. Participants receive a baseline dental inspection in nursery and an endpoint inspection in Primary 1 at the age of 5 years old. We will use primary and secondary outcome measures to compare the effectiveness of Duraphat® fluoride varnish plus treatment as usual with treatment as usual only in preventing any further dental decay. We will also undertake a full economic evaluation of the trial.

trial registrationThis study is registered at ClinicalTrials.gov. Number: NCT01674933 (24 August 2012).

Indexed as

Oral HealthCariostatic AgentsChild, PreschoolDental CariesFluoridesFluorides, TopicalHumansResearch DesignSchools, NurseryScotlandCariostatic AgentsFluoridesFluorides, Topical

Identifiers

PMID26681191
PMCPMC4683783
OpenAlexW2202735404

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.