Evidence map›Paper›PMID 26680560›Full record

ReviewTherapeutic advances in cardiovascular disease2017

Edoxaban in patients with atrial fibrillation.

Alon Eisen, Christian T Ruff

Abstract readReview
In one paragraph

Review in Therapeutic advances in cardiovascular disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Alon EisenBrigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Christian T RuffBrigham and Women's Hospital and Harvard Medical School Boston, TIMI Study Group, 350 Longwood Avenue, 1st Floor Offices, Boston, MA 02115, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Edoxaban, a direct factor Xa inhibitor, was extensively studied in the prevention and treatment of venous thromboembolism and in patients with nonvalvular atrial fibrillation (AF). The aim of this review is to focus specifically on the efficacy and safety profile of edoxaban in patients with AF from preclinical development through the phase III trial that led to regulatory approval.

Indexed as

Administration, OralAtrial FibrillationFactor Xa InhibitorsHumansPyridinesStrokeThiazolesedoxabanFactor Xa InhibitorsPyridinesThiazolesatrial fibrillationedoxabanfactor xa inhibitornon-vitamin K oral anticoagulantsNovel oral anticoagulants

Identifiers

PMID26680560
PMCPMC5942795

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.