ArticleProtoplasma2017
Characterisation of Arabidopsis calnexin 1 and calnexin 2 in the endoplasmic reticulum and at plasmodesmata.
Article in Protoplasma, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- A comparative meta-proteomic pipeline for the identification of plasmodesmata proteins and regulatory conditions in diverse plant species.BMC biology · 2022Pooled it
- Discrete and cell-specific hypoxic responses in Arabidopsis roots resolved by single-nuclei transcriptomics.The New phytologist · 2026Article
- Molecular cloning and the expression profile of two calnexin genes - CNX1 and CNX2 - during pollen development and pollen tube growth in Petunia.BMC plant biology · 2025Article
- Validating the utility of APEX2 for protein localization at nanometre resolution in plant cells.Plant biotechnology journal · 2025Article
- Heavy Metal-Associated Isoprenylated Plant Proteins (HIPPs) at Plasmodesmata: Exploring the Link between Localization and Function.Plants (Basel, Switzerland) · 2023Review
- In Depth Topological Analysis of Arabidopsis Mid-SUN Proteins and Their Interaction with the Membrane-Bound Transcription Factor MaMYB.Plants (Basel, Switzerland) · 2023Article
- Endoplasmic reticulum calnexins participate in the primary root growth response to phosphate deficiency.Plant physiology · 2023Article
- Long-term cold, freezing and drought: overlapping and specific regulatory mechanisms and signal transduction in tea plant (Frontiers in plant science · 2023Article
- Recent progress and perspectives on physiological and molecular mechanisms underlying cold tolerance of tea plants.Frontiers in plant science · 2023Review
- Proteomic profiling of plasma exosomes from patients with B-cell acute lymphoblastic leukemia.Scientific reports · 2022Article
- Arabidopsis HOPS subunit VPS41 carries out plant-specific roles in vacuolar transport and vegetative growth.Plant physiology · 2022Article
- Plasmodesmata Structural Components and Their Role in Signaling and Plant Development.Methods in molecular biology (Clifton, N.J.) · 2022Review
- Article
- Intercellular trafficking via plasmodesmata: molecular layers of complexity.Cellular and molecular life sciences : CMLS · 2021Review
- RabA2b Overexpression Alters the Plasma-Membrane Proteome and Improves Drought Tolerance in Arabidopsis.Frontiers in plant science · 2021Article
- Leaf Epidermis: The Ambiguous Symplastic Domain.Frontiers in plant science · 2021Article
- Genome-wide analysis ofPhysiology and molecular biology of plants : an international journal of functional plant biology · 2020Article
- CytochromeThe Plant cell · 2019Article
- A Split-GFP Gateway Cloning System for Topology Analyses of Membrane Proteins in Plants.PloS one · 2017Article
- Comparative Lipidomics and Proteomics of Lipid Droplets in the Mesocarp and Seed Tissues of Chinese Tallow (Frontiers in plant science · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Calnexin (CNX) is a highly conserved endoplasmic reticulum (ER) chaperone protein. Both calnexin and the homologous ER-lumenal protein, calreticulin, bind calcium ions and participate in protein folding. There are two calnexins in Arabidopsis thaliana, CNX1 and CNX2. GUS expression demonstrated that these are expressed in most Arabidopsis tissues throughout development. Calnexin transfer DNA (T-DNA) mutant lines exhibited increased transcript abundances of a number of other ER chaperones, including calreticulins, suggesting a degree of redundancy. CNX1 and CNX2 localised to the ER membrane including that within plasmodesmata, the intercellular channels connecting plant cells. This is comparable with the previous localisations of calreticulin in the ER lumen and at plasmodesmata. However, from green fluorescent protein (GFP) diffusion studies in single and double T-DNA insertion mutant lines, as well as overexpression lines, we found no evidence that CNX1 or CNX2 play a role in intercellular transport through plasmodesmata. In addition, calnexin T-DNA mutant lines showed no change in transcript abundance of a number of plasmodesmata-related proteins. CNX1 and CNX2 do not appear to have a specific localisation or function at plasmodesmata-rather the association of calnexin with the ER is simply maintained as the ER passes through plasmodesmata.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.