Evidence map›Paper›PMID 26679768›Full record

Trial reportTrials2015

Informal Health Provider and Practical Approach to Lung Health interventions to improve the detection of chronic airways disease and tuberculosis at primary care level in Malawi: study protocol for a randomised controlled trial.

Hastings T Banda, Kevin Mortimer, George A F Bello, Grace B Mbera, Ireen Namakhoma, Rachael Thomson, Moffat J Nyirenda, Brian Faragher, Jason Madan, Rasmus Malmborg and 6 more

Abstract readComparative StudyMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Trials, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Hastings T BandaResearch for Equity and Community Health Trust, ᅟ, Malawi. hastings@reachtrust.org.
Kevin MortimerLiverpool School of Tropical Medicine, Liverpool, UK. kevin.mortomer@lstmed.ac.uk.
George A F BelloResearch for Equity and Community Health Trust, ᅟ, Malawi. gafbello@yahoo.co.uk.
Grace B MberaResearch for Equity and Community Health Trust, ᅟ, Malawi. grace@reachtrust.org.
Ireen NamakhomaResearch for Equity and Community Health Trust, ᅟ, Malawi. ireen@reachtrust.org.
Rachael ThomsonLiverpool School of Tropical Medicine, Liverpool, UK. Rachael.Thomson@lstmed.ac.uk.
Moffat J NyirendaCollege of Medicine, Mahatma Gandhi, Blantyre, Malawi. moffat.nyirenda@lshtm.ac.uk.
Brian FaragherLiverpool School of Tropical Medicine, Liverpool, UK. brian.faragher@lstmed.ac.uk.
Jason MadanWarwick University, Coventry, CV4 7AL, UK. J.J.Madan@warwick.ac.uk.
Rasmus MalmborgLHL International, Grensen 3, 0159, Oslo, Norway. rasmus.malmborg@lhl.no.
Berthe StenbergLHL International, Grensen 3, 0159, Oslo, Norway. Berthe.Stenberg@lhl.no.
James MpungaMinistry of Health, 30377, Capital City, Lilongwe 3, Malawi. jmpunga@ntpmalawi.org.
Beatrice MwagombaMinistry of Health, 30377, Capital City, Lilongwe 3, Malawi. mwagombabeatrice@yahoo.com.
Elvis GamaLiverpool School of Tropical Medicine, Liverpool, UK. elvis.gama@lstmed.ac.uk.
Katherine PiddockLiverpool School of Tropical Medicine, Liverpool, UK. kpiddock@doctors.org.uk.
Stephen B SquireLiverpool School of Tropical Medicine, Liverpool, UK.

Funding

Medical Research Council MR/L002515/1
6 · The paper itself

Abstract

backgroundIn developing countries like Malawi, further investigation is rare after patients with chronic cough test negative for tuberculosis. Chronic airways disease has presentations that overlap with tuberculosis. However, chronic airways disease is often unrecognised due to a lack of diagnostic services. Within developing countries, referral systems at primary health care level are weak and patients turn to unskilled informal health providers to seek health care. Delayed diagnosis and treatment of these diseases facilitates increased severity and tuberculosis transmission. The World Health Organisation developed the Practical Approach to Lung Health strategy which has been shown to improve the management of both tuberculosis and chronic airways disease. The guidelines address the need for integrated guidelines for tuberculosis and chronic airways disease. Engaging with informal health providers has been shown to be effective in improving health services uptake. However, it is not known whether engaging community informal health providers would have a positive impact in the implementation of the Practical Approach to Lung Health strategy. We will use a cluster randomised controlled trial to determine the effect of using the two interventions to improve case detection and treatment of patients with tuberculosis and chronic airways disease.

methodsA three-arm cluster randomised trial design will be used. A primary health centre catchment population will form a cluster, which will be randomly allocated to one of the arms. The first arm personnel will receive the Practical Approach to Lung Health strategy intervention. In addition to this strategy, the second arm personnel will receive training of informal health providers. The third arm is the control. The effect of interventions will be evaluated by community surveys. Data regarding the diagnosis and management of chronic cough will be gathered from primary health centres. DISCUSSION: This trial seeks to determine the effect of Informal Health Provider and Practical Approach to Lung Health interventions on the detection and management of chronic airways disease and tuberculosis at primary care level in Malawi.

trial registrationThe unique identification number for the registry is PACTR201411000910192--21 November 2014.

Indexed as

Community Health ServicesHealth PersonnelPatient CarePrimary Health CareChronic DiseaseCoughCritical PathwaysDelayed DiagnosisDelivery of Health Care, IntegratedDeveloping CountriesHumansLung DiseasesMalawiPractice Guidelines as TopicPredictive Value of TestsPrognosis

Identifiers

PMID26679768
PMCPMC4683704

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.