ArticleScientific reports2015
Monitor unit optimization in stereotactic body radiotherapy for small peripheral non-small cell lung cancer patients.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Impact of monitor unit optimization in volumetric modulated arc therapy planning for nasopharyngeal carcinoma.PloS one · 2025Article
- On the reduction of aperture complexity in kidney SABR.Journal of applied clinical medical physics · 2021Article
- Assessment of the Monitor Unit Objective tool for VMAT in the Eclipse treatment planning system.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation OncologyArticle
- Performance of the eclipse monitor unit objective tool utilizing volumetric modulated arc therapy for rectal cancer.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation OncologyArticle
- Photon and Neutron Dose Estimation Using Monte Carlo Simulation in TrueBeam's Room.Journal of medical physicsArticle
- Effect of Multi-Leaf Collimator Angle Optimization on the Planning Parameters in Intensity-Modulated Radiotherapy for Thoracic Tumors.Technology in cancer research & treatmentArticle
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Authors and funding
5 authors.
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Abstract
The increasingly attractive stereotactic body radiotherapy (SBRT) treatment for stage I lung cancer is concomitant with a large amount of monitor units (MU), leading to excessive out-of-field dose and prolonged beam-on time. The study aims to reduce the MU number and shorten the beam-on time by optimizing the planning parameters. Clinically acceptable treatment plans from fourteen patients suffered from peripheral stage I non-small cell lung cancer (NSCLC) were created in the study. Priority for the upper objective of the target (PUOT), strength and Max MU setting in the MU objective function (MUOF) were adjusted respectively to investigate their effect on MU number, organs at risk (OARs) sparing and beam-on time. We found that the planning parameters influenced the MU number in a PUOT, strength and Max MU dependent manner. Combined with high priority for the UOT (HPUOT) and MUOF, the MU number was reduced from 443 ± 25 to 228 ± 22 MU/Gy without compromising the target coverage and OARs sparing. We also found beam-on time was proportional to MU number and it could be shortened from 7.9 ± 0.5 to 4.1 ± 0.4 minutes.
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