Evidence map›Paper›PMID 26679536›Full record

ArticleThe journal of spinal cord medicine2016

Seronegative neuromyelitis optica presenting with life-threatening respiratory failure.

Raffaele Nardone, Giulio Zuccoli, Francesco Brigo, Eugen Trinka, Ryan T Fitzgerald

Open access · greenAbstract readCase Reports
In one paragraph

Article in The journal of spinal cord medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 3 countries.

Raffaele Nardonea Department of Neurology, Christian Doppler Klinik , Paracelsus Medical University , Salzburg , Austria.
Giulio Zuccolic Children's Hospital of Pittsburgh at the University of Pittsburgh Medical Center , Pennsylvania , USA.
Francesco Brigob Department of Neurology , Franz Tappeiner Hospital , Merano , Italy.
Eugen Trinkaa Department of Neurology, Christian Doppler Klinik , Paracelsus Medical University , Salzburg , Austria.
Ryan T Fitzgeralde University of Arkansas for Medical Sciences , Little Rock , USA.
Children's Hospital of Pittsburgh · USChristian Doppler Klinik · ATParacelsus Medical University · ATUniversity of Arkansas for Medical Sciences · USUniversity of Verona · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextDyspnea has rarely been reported as a presenting symptom in patients with neuromyelitis optica (NMO). We report an unusual case of NMO relapse presenting with rapidly progressive respiratory failure and briefly discuss the possible pathophysiological mechanisms of this potential life-threatening complication of NMO.

findingsThe 58-year-old woman with a history of bilateral optic neuritis presented to the emergency department with rapidly worsening dyspnea. Cervical spine magnetic resonance imaging showed extensive abnormal signal with involvement of the medulla oblongata. Since in our patient chest radiography failed to disclose a diaphragmatic palsy that is commonly observed in patients with phrenic nerve involvement, this acute manifestation of the disease may be attributed to brainstem involvement instead of cervical myelitis. CONCLUSION/CLINICAL RELEVANCE: Clinicians should be aware of this atypical presentation of NMO, which needs to be promptly recognized and aggressively treated.

Indexed as

Brain StemFemaleHumansMiddle AgedNeuromyelitis OpticaRespiratory InsufficiencySerologic TestsSpinal CordAnti-aquaporin-4 antibodiesBrainstemCervical spineNeuromyelitis opticaRespiratory failure

Identifiers

PMID26679536
PMCPMC5137568
OpenAlexW2221011838

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.