ArticleBMC infectious diseases2015
Increased norovirus activity was associated with a novel norovirus GII.17 variant in Beijing, China during winter 2014-2015.
Article in BMC infectious diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- Pooled prevalence and genetic diversity of norovirus in Africa: a systematic review and meta-analysis.Virology journal · 2022Pooled it
- Molecular genetic characterisation of norovirus GII.17 strains circulating in South Korea in 2024.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2026Article
- 24-Epibrassinolide-Succinic Acid Conjugate Is Involved in the Acclimation of Rape Plants to Salt Stress.Plants (Basel, Switzerland) · 2025Article
- Emergence of norovirus GII.17[P16] in adult patients with acute gastroenteritis in Thailand during 2021-2023.PloS one · 2025Article
- The genetic diversity of genogroup I noroviruses causing acute gastroenteritis outbreaks in Beijing between 2014 and 2023.Heliyon · 2024Article
- Predominance of Recombinant Norovirus Strains in Greece, 2016-2018.Microorganisms · 2023Article
- Epidemiology and genetic diversity of norovirus GII genogroups among children in Hubei, China, 2017-2019.Virologica Sinica · 2023Article
- Changing Predominance of Norovirus Recombinant Strains GII.2[P16] to GII.4[P16] and GII.4[P31] in Thailand, 2017 to 2018.Microbiology spectrum · 2022Article
- Epidemiological characteristics and genetic diversity of norovirus infections among outpatient children with diarrhea under 5 years of age in Beijing, China, 2011-2018.Gut pathogens · 2021Article
- Norovirus Activity and Genotypes in Sporadic Acute Diarrhea in Children in Shanghai During 2014-2018.The Pediatric infectious disease journal · 2019Article
- Variation of human norovirus GII genotypes detected in Ibaraki, Japan, during 2012-2018.Gut pathogens · 2019Article
- Article
- The prevalence of non-GII.4 norovirus genotypes in acute gastroenteritis outbreaks in Jinan, China.PloS one · 2018Article
- Phylogenetic characterization of norovirus strains detected from sporadic gastroenteritis in Seoul during 2014-2016.Gut pathogens · 2018Article
- Full-genome sequence analysis of an uncommon norovirus genotype, GII.21, from South Korea.Epidemiology and infection · 2017Article
- Global Spread of Norovirus GII.17 Kawasaki 308, 2014-2016.Emerging infectious diseases · 2017Article
- Deep sequencing of phage-displayed peptide libraries reveals sequence motif that detects norovirus.Protein engineering, design & selection : PEDS · 2017Article
- The transmissibility of noroviruses: Statistical modeling of outbreak events with known route of transmission in Japan.PloS one · 2017Article
- Norovirus genotype distribution in outbreaks of acute gastroenteritis among children and older people: an 8-year study.BMC infectious diseases · 2016Article
- Emergence of human caliciviruses among diarrhea cases in southwest China.BMC infectious diseases · 2016Article
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11 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNorovirus (NoV) is a leading cause of sporadic cases and outbreaks of acute gastroenteritis (AGE). Increased NoV activity was observed in Beijing, China during winter 2014-2015; therefore, we examined the epidemiological patterns and genetic characteristics of NoV in the sporadic cases and outbreaks.
methodsThe weekly number of infectious diarrhea cases reported by all hospitals in Beijing was analyzed through the China information system for disease control and prevention. Fecal specimens were collected from the outbreaks and outpatients with AGE, and GI and GII NoVs were detected using real time reverse transcription polymerase chain reaction. The partial capsid genes and RNA-dependent RNA polymerase (RdRp) genes of NoV were both amplified and sequenced, and genotyping and phylogenetic analyses were performed.
resultsBetween December 2014 and March 2015, the number of infectious diarrhea cases in Beijing (10,626 cases) increased by 35.6% over that of the previous year (7835 cases), and the detection rate of NoV (29.8%, 191/640) among outpatients with AGE was significantly higher than in the previous year (12.9%, 79/613) (χ(2) = 53.252, P < 0.001). Between November 2014 and March 2015, 35 outbreaks of AGE were reported in Beijing, and NoVs were detected in 33 outbreaks, all of which belonged to the GII genogroup. NoVs were sequenced and genotyped in 22 outbreaks, among which 20 were caused by a novel GII.17 strain. Among outpatients with AGE, this novel GII.17 strain was first detected in an outpatient in August 2014, and it replaced GII.4 Sydney_2012 as the predominant variant between December 2014 and March 2015. A phylogenetic analysis of the capsid genes and RdRp genes revealed that this novel GII.17 strain was distinct from previously identified GII variants, and it was recently designated as GII.P17_GII.17. This variant was further clustered into two sub-groups, named GII.17_2012 and GII.17_2014. During winter 2014-2015, GII.17_2014 caused the majority of AGE outbreaks in China and Japan.
conclusionsDuring winter 2014-2015, a novel NoV GII.17 variant replaced the GII.4 variant Sydney 2012 as the predominant strain in Beijing, China and caused increased NoV activity.
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