Evidence map›Paper›PMID 26678806›Full record

ArticleImmunology2016

Reproducibility and conflicts in immune epitope data.

Randi Vita, Nicole Vasilevsky, Anita Bandrowski, Melissa Haendel, Alessandro Sette, Bjoern Peters

Abstract read
In one paragraph

Article in Immunology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Minimal Information about MHC Multimers (MIAMM).Journal of immunology (Baltimore, Md. : 1950) · 2022
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Randi VitaDivision of Vaccine Discovery, La Jolla Institute for Allergy & Immunology, La Jolla, CA, USA.ORCID http://orcid.org/0000-0001-8957-7612
Nicole VasilevskyOntology Development Group, Oregon Health & Science University, Portland, OR, USA.
Anita BandrowskiNeuroscience Information Framework, University of California, San Diego, San Diego, CA, USA.
Melissa HaendelOntology Development Group, Oregon Health & Science University, Portland, OR, USA.
Alessandro SetteDivision of Vaccine Discovery, La Jolla Institute for Allergy & Immunology, La Jolla, CA, USA.
Bjoern PetersDivision of Vaccine Discovery, La Jolla Institute for Allergy & Immunology, La Jolla, CA, USA.

Funding

NIDDK Network Coordinating UnitU24DK097771 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Shuibing Chen, Jeffrey S. Grethe · 2013 to 2026
$20.9M
The Monarch Initiative: Linking Diseases to Model Organism ResourcesR24OD011883 · OD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HAENDEL, MELISSA A, MUNGALL, CHRISTOPHER J · 2012 to 2024
$16.0M
OPERATION, SUPPORT AND STRATEGIC ENHANCEMENT OF THE NEUROSCIENCE INFORMATION FRAMEWORKU24DA039832 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GRETHE, JEFFREY S., MARTONE, MARYANN E · 2015 to 2016
$2.0M
NIDA NIH HHS U24 DA039832NIDDK NIH HHS U24 DK097771NIH HHS R24 OD011883
6 · The paper itself

Abstract

The Immune Epitope Database is uniquely positioned to assess the body of research related to immune epitopes, we have manually curated all such published data. Thus, we are able to make observations on the state of these fields of research, as well as aggregate the individual data points to present a clearer picture of the immune response to specific antigens in all studied hosts. Additionally, we are able to identify where conflicts in the literature exist and where publications fall short in terms of identifiable methods and in reproducibility. Here we present guidelines to improve the quality of immune epitope data, which will benefit journals and researchers alike.

Indexed as

Allergy and ImmunologyDatabases, ProteinEpitopesHumansReproducibility of ResultsEpitopesdatabaseimmune epitopeImmune Epitope Databasereproducibility

Identifiers

PMID26678806
PMCPMC4754615

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.