Evidence map›Paper›PMID 26678638›Full record

ArticleAmerican heart journal2015

Hospital variation in admission to intensive care units for patients with acute myocardial infarction.

RuiJun Chen, Kelly M Strait, Kumar Dharmarajan, Shu-Xia Li, Isuru Ranasinghe, John Martin, Reza Fazel, Frederick A Masoudi, Colin R Cooke, Brahmajee K Nallamothu and 1 more

Abstract read
In one paragraph

Article in American heart journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 46 citations in OpenAlex.

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  7. Injury outcomes across Canadian trauma systems: a historical cohort study.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2023
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 10 institutions in 2 countries.

RuiJun ChenUniversity of California San Francisco, San Francisco, CA.
Kelly M StraitCenter for Outcomes Research and Evaluation, Yale-New Haven Hospital, New Haven, CT.
Kumar DharmarajanCenter for Outcomes Research and Evaluation, Yale-New Haven Hospital, New Haven, CT; Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT.
Shu-Xia LiCenter for Outcomes Research and Evaluation, Yale-New Haven Hospital, New Haven, CT.
Isuru RanasingheUniversity of Sydney, Sydney, NSW, Australia.
John MartinPremier Inc, Washington, DC.
Reza FazelBrigham and Women's Hospital and Harvard Medical School, Boston, MA.
Frederick A MasoudiDivision of Cardiology, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO.
Colin R CookeDivision of Pulmonary & Critical Care Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, MI; Center for Healthcare Outcomes and Policy, University of Michigan, Ann Arbor, MI.
Brahmajee K NallamothuCenter for Healthcare Outcomes and Policy, University of Michigan, Ann Arbor, MI; Veterans Affairs (VA) Health Services Research and Development Center of Excellence, VA Ann Arbor Healthcare System, Ann Arbor, MI.
Harlan M KrumholzCenter for Outcomes Research and Evaluation, Yale-New Haven Hospital, New Haven, CT; Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT; Robert Wood Johnson Foundation Clinical Scholars Program, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT; Department of Health Policy and Management, Yale School of Public Health, New Haven, CT. Electronic address: harlan.krumholz@yale.edu.
Yale New Haven Hospital · USBrigham and Women's Hospital · USPremier Research Group · USUniversity of California, San Francisco · USUniversity of Colorado Anschutz Medical Campus · USUniversity of Michigan–Ann Arbor · USUniversity of Sydney · AUVA Ann Arbor Healthcare System · USYale New Haven Health System · USYale University · US

Funding

YALE UNIVERSITY CLINICAL AND TRANSLATIONAL SCIENCE AWARD PROGRAMUL1RR024139 · NCRR · YALE UNIVERSITY · PI SHERWIN, ROBERT S · 2006 to 2011
$56.8M
Center for Cardiovascular Outcomes Research at Yale UniversityU01HL105270 · NHLBI · YALE UNIVERSITY · PI CURTIS, JEPTHA PELHAM, KRUMHOLZ, HARLAN MARC · 2010 to 2013
$5.8M
Understanding Variation in the Use of Critical Care ServicesK08HS020672 · AHRQ · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI COOKE, COLIN · 2012 to 2016
$768k
AHRQ HHS K08 HS020672NCRR NIH HHS UL1 RR024139NCRR NIH HHS UL1 RR024139-06S1NHLBI NIH HHS U01 HL105270NHLBI NIH HHS U01 HL105270-05
6 · The paper itself

Abstract

backgroundThe treatment for patients with acute myocardial infarction (AMI) was transformed by the introduction of intensive care units (ICUs), yet we know little about how contemporary hospitals use this resource-intensive setting and whether higher use is associated with better outcomes.

methodsWe identified 114,136 adult hospitalizations for AMI from 307 hospitals in the 2009 to 2010 Premier database using codes from the International Classification of Diseases, Ninth Revision, Clinical Modification. Hospitals were stratified into quartiles by rates of ICU admission for AMI patients. Across quartiles, we examined in-hospital risk-standardized mortality rates and usage rates of critical care therapies for these patients.

resultsRates of ICU admission for AMI patients varied markedly among hospitals (median 48%, Q1-Q4 20%-71%, range 0%-98%), and there was no association with in-hospital risk-standardized mortality rates (6% all quartiles, P = .7). However, hospitals admitting more AMI patients to the ICU were more likely to use critical care therapies overall (mechanical ventilation [from Q1 with lowest rate of ICU use to Q4 with highest rate 13%-16%], vasopressors/inotropes [17%-21%], intra-aortic balloon pumps [4%-7%], and pulmonary artery catheters [4%-5%]; P for trend < .05 in all comparisons).

conclusionsRates of ICU admission for patients with AMI vary substantially across hospitals and were not associated with differences in mortality, but were associated with greater use of critical care therapies. These findings suggest uncertainty about the appropriate use of this resource-intensive setting and a need to optimize ICU triage for patients who will truly benefit.

Indexed as

Anterior Wall Myocardial InfarctionCoronary Care UnitsAdultAgedAged, 80 and overHealth Care RationingHospital MortalityHumansLength of StayMaleMiddle AgedOutcome and Process Assessment, Health CarePatient AdmissionQuality ImprovementRetrospective StudiesRisk Assessment

Identifiers

PMID26678638
PMCPMC5459386
OpenAlexW2099122036

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.