Evidence map›Paper›PMID 26678622›Full record

ArticleHeadache2016

Cyclic vomiting syndrome versus inborn errors of metabolism: A review with clinical recommendations.

Amy A Gelfand, Renata C Gallagher

Abstract read
In one paragraph

Article in Headache, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 30 citations in OpenAlex.

  1. Eu- or hypoglycemic ketosis and ketoacidosis in children: a review.Pediatric nephrology (Berlin, Germany) · 2024
    Review
  2. Article
  3. Review
  4. Review
  5. Yield and Costs of Evaluating Children With Cyclic Vomiting Syndrome.Journal of pediatric gastroenterology and nutrition · 2018
    Article
  6. Cyclic Vomiting Syndrome in Children.Current pain and headache reports · 2018
    Review
  7. Review
  8. Review
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Amy A GelfandDepartment of Neurology, UCSF, San Francisco, CA, USA.
Renata C GallagherDepartment of Pediatrics, UCSF, San Francisco, CA, USA.
University of California San Francisco Medical Center · US

Funding

Clinical and Transtional Science InstituteKL2TR000143 · NCATS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GRANDIS, JENNIFER RUBIN · 2012 to 2015
$11.9M
NCATS NIH HHS 8KL2TR000143-09NCATS NIH HHS KL2 TR000143
6 · The paper itself

Abstract

backgroundInborn errors of metabolism are on the differential for patients presenting with a cyclic vomiting syndrome phenotype. Classes of disorders to consider include: mitochondrial disorders, fatty acid oxidation disorders, urea cycle defects, organic acidurias, and acute intermittent porphyria.

aimThis article reviews the metabolic differential diagnosis and approach to screening for inborn errors in children and adults presenting with a cyclic or recurrent vomiting phenotype.

conclusionCyclic vomiting syndrome is thought to be an episodic syndrome that may be associated with migraine. It is a diagnosis of exclusion. Inborn errors of metabolism should be considered in the patient presenting with a recurrent vomiting phenotype. Mitochondrial dysfunction may play a role in cyclic vomiting syndrome, and true mitochondrial disorders can present with a true cyclic vomiting phenotype.

Indexed as

HumansLipid Metabolism, Inborn ErrorsPhenotypeVomitingabdominal migrainecyclic vomiting syndromeinborn error of metabolismmitochondriopathy

Identifiers

PMID26678622
PMCPMC4728152
OpenAlexW2205012455

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.