ArticleCancer cell2015
Immunotherapy Not Working? Check Your Microbiota.
Article in Cancer cell, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed.
- Ulcerative Colitis after Administration of Dupilumab, an Anti-interleukin-4 Receptor Subunit α Monoclonal Antibody.Internal medicine (Tokyo, Japan) · 2026Article
- Synergy betweenMolecular therapy. Methods & clinical development · 2024Article
- Inflammation and cancer: friend or foe?Frontiers in pharmacology · 2024Review
- Characterization of Gut Microbiome Composition in Patients with Triple-Negative Breast Cancer Treated with Neoadjuvant Chemotherapy.The oncologist · 2023Article
- Microbiota-Derived Natural Products Targeting Cancer Stem Cells: Inside the Gut Pharma Factory.International journal of molecular sciences · 2023Review
- Gut microbiome and serum short-chain fatty acids are associated with responses to chemo- or targeted therapies in Chinese patients with lung cancer.Frontiers in microbiology · 2023Article
- The role of gut microbiota in the development of colorectal cancer: a review.International journal of colorectal disease · 2022Review
- Microbiota and Hematological Diseases.International journal of hematology-oncology and stem cell research · 2022Review
- The cure from within? a review of the microbiome and diet in melanoma.Cancer metastasis reviews · 2022Review
- Faecal microbiota transplantation enhances efficacy of immune checkpoint inhibitors therapy against cancer.World journal of gastroenterology · 2021Review
- Exploring the Role of Gut Microbiome in Colon Cancer.Applied biochemistry and biotechnology · 2021Review
- Dietary Regulation of the Crosstalk between Gut Microbiome and Immune Response in Inflammatory Bowel Disease.Foods (Basel, Switzerland) · 2021Review
- Systemic Immunoregulatory Consequences of Gut Commensal Translocation.Trends in immunology · 2021Review
- Gut microbiota influence tumor development and Alter interactions with the human immune system.Journal of experimental & clinical cancer research : CR · 2021Review
- Airway Microbiota as a Modulator of Lung Cancer.International journal of molecular sciences · 2020Review
- An Integrated Multi-Disciplinary Perspectivefor Addressing Challenges of the Human Gut Microbiome.Metabolites · 2020Review
- Intestinal Bacteria Encapsulated by Biomaterials Enhance Immunotherapy.Frontiers in immunology · 2020Review
- Immunotherapy in the Treatment of Metastatic Melanoma: Current Knowledge and Future Directions.Journal of immunology research · 2020Review
- Microbiome and colorectal cancer: Roles in carcinogenesis and clinical potential.Molecular aspects of medicine · 2019Review
- Probiotic Bacteria: A Promising Tool in Cancer Prevention and Therapy.Current microbiology · 2019Review
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Gut microbes have ascended to prominence as key modulators of host immunity, raising the possibility that they could influence the outcome of cancer immunotherapy. Two recent studies address this question by identifying specific gut-resident bacteria as drivers of checkpoint blockade immunotherapy in pre-clinical tumor models.
Indexed as
Identifiers
26678336What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.