ArticleOptica2015
Focusing through dynamic tissue with millisecond digital optical phase conjugation.
Article in Optica, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
65 citing papers in PubMed.
- Focusing scattered light through live tissue with channel-selected wavefront shaping.Biomedical optics express · 2026Article
- Article
- Optical focusing into scattering media via iterative time reversal guided by absorption nonlinearity.Nature communications · 2025Article
- Threading light through dynamic complex media.Nature photonics · 2025Article
- Ultrafast adaptive optics for imaging the living human eye.Nature communications · 2024Article
- All-optical phase conjugation using diffractive wavefront processing.Nature communications · 2024Article
- Article
- Performance enhancement in wavefront shaping of multiply scattered light: a review.Journal of biomedical optics · 2024Review
- Fast wavefront shaping for two-photon brain imaging with multipatch correction.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Formation of multiple complex light structures simultaneously in 3D volume using a single binary phase mask.Scientific reports · 2023Article
- High-gain and high-speed wavefront shaping through scattering media.Nature photonics · 2023Article
- Optical trapping with holographically structured light for single-cell studies.Biophysics reviews · 2023Review
- High-speed single-exposure time-reversed ultrasonically encoded optical focusing against dynamic scattering.Science advances · 2022Article
- Wavefront shaping: A versatile tool to conquer multiple scattering in multidisciplinary fields.Innovation (Cambridge (Mass.)) · 2022Review
- Ultrathin, high-speed, all-optical photoacoustic endomicroscopy probe for guiding minimally invasive surgery.Biomedical optics express · 2022Article
- Imaging Dynamics Beneath Turbid Media via Parallelized Single-Photon Detection.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022Article
- Real-time complex light field generation through a multi-core fiber with deep learning.Scientific reports · 2022Article
- Enhance the delivery of light energy ultra-deep into turbid medium by controlling multiple scattering photons to travel in open channels.Light, science & applications · 2022Article
- Neurophotonic tools for microscopic measurements and manipulation: status report.Neurophotonics · 2022Article
- High speed, complex wavefront shaping using the digital micro-mirror device.Scientific reports · 2021Article
5 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Digital optical phase conjugation (DOPC) is a new technique employed in wavefront shaping and phase conjugation for focusing light through or within scattering media such as biological tissues. DOPC is particularly attractive as it intrinsically achieves a high fluence reflectivity in comparison to nonlinear optical approaches. However, the slow refresh rate of liquid crystal spatial light modulators and limitations imposed by computer data transfer speeds have thus far made it difficult for DOPC to achieve a playback latency of shorter than ~200 ms and, therefore, prevented DOPC from being practically applied to thick living samples. In this paper, we report a novel DOPC system that is capable of 5.3 ms playback latency. This speed improvement of almost 2 orders of magnitude is achieved by using a digital micromirror device, field programmable gate array (FPGA) processing, and a single-shot binary phase retrieval technique. With this system, we are able to focus through 2.3 mm living mouse skin with blood flowing through it (decorrelation time ~30 ms) and demonstrate that the focus can be maintained indefinitely-an important technological milestone that has not been previously reported, to the best of our knowledge.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.