Evidence map›Paper›PMID 26677379›Full record

ArticlePostepy w kardiologii interwencyjnej = Advances in interventional cardiology2015

Investigation of ischemia modified albumin, oxidant and antioxidant markers in acute myocardial infarction.

Ahmet Hazini, Mustafa Cemek, İbrahim Işıldak, Saadet Alpdağtaş, Abdullah Önül, Ünal Şenel, Tuba Kocaman, Ali Dur, Mustafa Iraz, Hüseyin Uyarel

Open access · goldAbstract read
In one paragraph

Article in Postepy w kardiologii interwencyjnej = Advances in interventional cardiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
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  10. Prognostic significance of ischemia-modified albumin for severe acute pancreatitis.International journal of clinical and experimental pathology · 2017
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Ahmet HaziniDepartment of Bioengineering (Biochemistry Division), Chemical and Metallurgical Engineering Faculty, Yıldız Technical University, Istanbul, Turkey.
Mustafa CemekDepartment of Bioengineering (Biochemistry Division), Chemical and Metallurgical Engineering Faculty, Yıldız Technical University, Istanbul, Turkey.
İbrahim IşıldakDepartment of Bioengineering (Biochemistry Division), Chemical and Metallurgical Engineering Faculty, Yıldız Technical University, Istanbul, Turkey.
Saadet AlpdağtaşDepartment of Bioengineering (Biochemistry Division), Chemical and Metallurgical Engineering Faculty, Yıldız Technical University, Istanbul, Turkey.
Abdullah ÖnülDepartment of Bioengineering (Biochemistry Division), Chemical and Metallurgical Engineering Faculty, Yıldız Technical University, Istanbul, Turkey.
Ünal ŞenelDepartment of Bioengineering (Biochemistry Division), Chemical and Metallurgical Engineering Faculty, Yıldız Technical University, Istanbul, Turkey.
Tuba KocamanDepartment of Bioengineering (Biochemistry Division), Chemical and Metallurgical Engineering Faculty, Yıldız Technical University, Istanbul, Turkey.
Ali DurDepartment of Emergency, Faculty of Medicine, Bezmialem Vakıf University, Istanbul, Turkey.
Mustafa IrazDepartment of Pharmacology, Faculty of Medicine, Istanbul Medeniyet University, Istanbul, Turkey.
Hüseyin UyarelDepartment of Cardiology, Faculty of Medicine, Bezmialem Vakif University, Istanbul, Turkey.
Yıldız Technical University · TRBezmiâlem Vakıf Üniversitesi · TRIstanbul Medeniyet University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAcute myocardial infarction (AMI) is still one of the most common causes of death worldwide. In recent years, for diagnosis of myocardial ischemia, a new parameter, called ischemia modified albumin (IMA), which is thought to be more advantageous than common methods, has been researched.

aimIn this study, systematic analysis of parameters considered to be related to myocardial ischemia has been performed, comparing between control and myocardial ischemia groups. MATERIAL AND

methodsWe selected 40 patients with AMI and 25 healthy controls for this study. Ischemia modified albumin levels, glutathione peroxidase (GPx), superoxide dismutase (SOD), and catalase (CAT) antioxidant enzyme activities and non-enzymatic antioxidants such as retinol, α-tocopherol, β-carotene and ascorbic acid levels were investigated in both groups. Glutathione (GSH) and malondialdehyde (MDA) levels, which are indicators of oxidative stress, were compared between patient and control groups.

resultsIschemia modified albumin levels were found significantly higher in the AMI diagnosed group when compared with controls. The MDA level was elevated in the patient group, whereas the GSH level was decreased. SOD, GPx and CAT enzyme levels were decreased in the patient group, where it could be presumed that oxidative stress causes the cardiovascular diseases.

conclusionsDue to the increased oxidative stress, non-enzymatic and enzymatic antioxidant capacity was affected. Systematic investigation of parameters related to myocardial infarction has been performed, and it is believed that such parameters can contribute to protection and early diagnosis of AMI and understanding the mechanism of development of the disease.

Indexed as

enzymatic and non-enzymatic antioxidantsischemia modified albuminmyocardial infarctionoxidative stress

Identifiers

PMID26677379
PMCPMC4679797
OpenAlexW2322459567

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.