Evidence map›Paper›PMID 26677246›Full record

ArticleJournal of clinical microbiology2016

Impact of Variations in Test Method Parameters on In Vitro Activity of Surotomycin against Clostridium difficile and Surotomycin Quality Control Limits for Broth Microdilution and Agar Dilution Susceptibility Testing.

Maria M Traczewski, Jennifer Deane, Daniel Sahm, Steven D Brown, Laurent Chesnel

Abstract read
In one paragraph

Article in Journal of clinical microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Maria M TraczewskiClinical Microbiology Institute, Wilsonville, Oregon, USA.
Jennifer DeaneEurofins Medinet, Chantilly, Virginia, USA.
Daniel SahmEurofins Medinet, Chantilly, Virginia, USA.
Steven D BrownClinical Microbiology Institute, Wilsonville, Oregon, USA.
Laurent ChesnelMerck and Co., Inc., Kenilworth, New Jersey, USA laurent.chesnel@merck.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Test parameter variations were evaluated for their effects on surotomycin MICs. Calcium concentration was the only variable that influenced MICs; therefore, 50 μg/ml (standard for lipopeptide testing) is recommended. Quality control ranges for Clostridium difficile (0.12 to 1 μg/ml) and Eggerthella lenta (broth, 1 to 4 μg/ml; agar, 1 to 8 μg/ml) were approved by the Clinical and Laboratory Standards Institute based on these data.

Indexed as

Anti-Bacterial AgentsClostridioides difficileHumansLipopeptidesMicrobial Sensitivity TestsPeptides, CyclicQuality ControlReproducibility of ResultsSensitivity and SpecificityAnti-Bacterial AgentsCB-183,315LipopeptidesPeptides, Cyclic

Identifiers

PMID26677246
PMCPMC4767964

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.