Evidence map›Paper›PMID 26676336›Full record

ArticleEndocrinology and metabolism (Seoul, Korea)2016

Radiographic Characteristics of Adrenal Masses in Oncologic Patients.

Ji Hyun Lee, Eun Ky Kim, A Ram Hong, Eun Roh, Jae Hyun Bae, Jung Hee Kim, Chan Soo Shin, Seong Yeon Kim, Sang Wan Kim

Abstract read
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Article in Endocrinology and metabolism (Seoul, Korea), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

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0cells of the map it votes in
6citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Evaluation of quantitative parameters for distinguishing pheochromocytoma from other adrenal tumors.Hypertension research : official journal of the Japanese Society of Hypertension · 2018
    Article
  5. Articles in Endocrinology and Metabolism in 2016.Endocrinology and metabolism (Seoul, Korea) · 2017
    Article
  6. A CASE OF ADRENAL MYELOLIPOMA A PATIENT WITH BREAST CANCER.Acta endocrinologica (Bucharest, Romania : 2005)
    Article
4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Ji Hyun LeeDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
Eun Ky KimDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
A Ram HongDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
Eun RohDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
Jae Hyun BaeDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
Jung Hee KimDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
Chan Soo ShinDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
Seong Yeon KimDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
Sang Wan KimDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.ORCID http://orcid.org/0000-0001-9561-9110

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe aimed to assess the usefulness of pre-contrast Hounsfield unit (HU) and mass size on computed tomography to differentiate adrenal mass found incidentally in oncologic patients.

methodsFrom 2000 to 2012, 131 oncologic patients with adrenal incidentaloma were reviewed retrospectively. Receiver operating characteristic (ROC) curves were applied to determine the optimal cut-off value of the mean HU and size for detecting adrenal metastasis.

resultsThe median age was 18 years, and 80 patients were male. The initial mass size was 18 mm, and 71 (54.2%) of these were on the left side. A bilateral adrenal mass was found in 11 patients (8.4%). Biochemically functional masses were observed in 9.2% of patients. Thirty-six out of 119 patients with nonfunctional masses underwent adrenalectomy, which revealed metastasis in 13. The primary cancers were lung cancer (n=4), renal cell carcinoma (n=2), lymphoma (n=2), hepatocellular carcinoma (n=2), breast cancer (n=1), and others (n=2). The area under the curve for the size and HU for clinically suspicious metastasis were 0.839 (95% confidence interval [CI], 0.761 to 0.900; P<0.001) and 0.959 (95% CI, 0.898 to 0.988; P<0.001), respectively. The cut-off value to distinguish between metastasis and benign masses were 22 mm for size and 20 for HU.

conclusionROC curve results suggest that pre-contrast HU >20 can be used as a diagnostic reference to suggest metastasis in oncologic patients with adrenal masses.

Indexed as

Adrenal incidentalomaMetastasisNeoplasms

Identifiers

PMID26676336
PMCPMC4803551

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