ArticleWorld journal of gastroenterology2015
Effects of Ligustrum robustum on gut microbes and obesity in rats.
Article in World journal of gastroenterology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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10 citing papers in PubMed.
- Microbiota and mycobiota in bronchoalveolar lavage fluid of silicosis patients.Journal of occupational medicine and toxicology (London, England) · 2023Article
- Phenylethanoid and Phenylmethanoid Glycosides from the Leaves ofMolecules (Basel, Switzerland) · 2022Article
- Monoterpenoid Glycosides from the Leaves ofMolecules (Basel, Switzerland) · 2022Article
- Capsaicin regulates lipid metabolism through modulation of bile acid/gut microbiota metabolism in high-fat-fed SD rats.Food & nutrition research · 2022Article
- Preventive effect of small-leaved Kuding tea (Food science & nutrition · 2020Article
- Impact of dietary ingredients on the interpretation of various fecal parameters in rats fed inulin.Journal of food and drug analysis · 2019Article
- Involvement of the Hydroperoxy Group in the Irreversible Inhibition of Leukocyte-Type 12-Lipoxygenase by Monoterpene Glycosides Contained in the Qing Shan Lu Shui Tea.Molecules (Basel, Switzerland) · 2019Article
- Osteoarthritis Is a Low-Grade Inflammatory Disease: Obesity's Involvement and Herbal Treatment.Evidence-based complementary and alternative medicine : eCAM · 2019Review
- Cytoprotective Effect ofEvidence-based complementary and alternative medicine : eCAM · 2019Article
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9 authors.
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Abstract
aimTo investigate the anti-obesity and antibacterial effects of Ligustrum robustum (L. robustum) in vivo and in vitro and its possible mechanisms.
methodsThe effects of L. robustum aqueous extract (LR) on various gut bacteria in vitro were evaluated. The effects of LR on high-fat diet-fed (HFD) rats in vivo were also assessed. Culture methods, quantitative polymerase chain reaction, and terminal-restriction fragment length polymorphism were used to analyze the effects of LR on gut bacteria. Biochemical tests were also performed to detect the changes in obesity-related indicators after LR treatment.
resultsLR treatment lowered adipose weight and decreased Lee's index, blood glucose, total cholesterol, and lipid in the tested groups relative to control (P < 0.05). To determine the reasons for these changes, we assessed the potential bacteriostatic and bactericidal effects of LR on specific bacterial species in vitro. LR affected the richness, diversity, and evenness of gut bacteria, increased fecal Lactobacillus, and decreased Enterococci in HFD rats (P < 0.05).
conclusionL. robustum may be a safe and effective food for weight loss and obesity control, and the effects of L. robustum might be mediated by the regulation of gut bacteria.
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