Evidence map›Paper›PMID 26676226›Full record

ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2017

Acute changes in neurovascular reactivity after subarachnoid hemorrhage in vivo.

Matilde Balbi, Masayo Koide, Susanne M Schwarzmaier, George C Wellman, Nikolaus Plesnila

Open access · bronzeAbstract read
In one paragraph

Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Review
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  5. Article
  6. Review
  7. Role of endothelial nitric oxide synthase for early brain injury after subarachnoid hemorrhage in mice.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Long-term impairment of neurovascular coupling following experimental subarachnoid hemorrhage.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2020
    Article
  13. Article
  14. Article
  15. The yin and yang of KMicrocirculation (New York, N.Y. : 1994) · 2018
    Review
  16. Cerebrovascular Hemodynamics in Women.Seminars in neurology · 2017
    Review
  17. Inversion of neurovascular coupling after subarachnoid hemorrhage in vivo.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2017
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Matilde BalbiInstitute for Stroke and Dementia Research (ISD), University of Munich Medical Center, Munich, Germany.
Masayo KoideDepartment of Pharmacology, University of Vermont, Burlington, VT, USA.
Susanne M SchwarzmaierInstitute for Stroke and Dementia Research (ISD), University of Munich Medical Center, Munich, Germany.
George C WellmanDepartment of Pharmacology, University of Vermont, Burlington, VT, USA.
Nikolaus PlesnilaInstitute for Stroke and Dementia Research (ISD), University of Munich Medical Center, Munich, Germany nikolaus.plesnila@med.uni-muenchen.de.
Ludwig-Maximilians-Universität München · DEUniversity of Vermont · USMunich Cluster for Systems Neurology · DE

Funding

Impact of SAH on Parenchymal Arterioles and Neurovascular CouplingP01HL095488 · NHLBI · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI BONEV, ADRIAN · 2010 to 2014
$11.4M
Center for Neuroscience ExcellenceP30GM103498 · NIGMS · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI PARSONS, RODNEY L · 2012 to 2015
$4.3M
CENTER FOR NEUROSCIENCE EXCELLENCEP30RR032135 · NCRR · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI PARSONS, RODNEY L · 2011 to 2011
$1.1M
Acquisition of a Zeiss LSM 7 MP multiphoton microscopeS10OD010583 · OD · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI PARSONS, RODNEY L · 2012 to 2012
$599k
NCRR NIH HHS P30 RR032135NHLBI NIH HHS P01 HL095488NIGMS NIH HHS P30 GM103498NIH HHS S10 OD010583
6 · The paper itself

Abstract

Subarachnoid hemorrhage causes acute and long-lasting constrictions of pial arterioles. Whether these vessels dilate normally to neuronal activity is of great interest since a mismatch between delivery and consumption of glucose and oxygen may cause additional neuronal damage. Therefore, we investigated neurovascular reactivity of pial and parenchymal arterioles after experimental subarachnoid hemorrhage. C57BL/6 mice were subjected to subarachnoid hemorrhage by filament perforation or sham surgery. Neurovascular reactivity was assessed 3 h later by forepaw stimulation or inhalation of 10% CO

Indexed as

AnimalsArteriolesAstrocytesCalciumCarbon DioxideCell CommunicationMiceMice, Inbred C57BLNeuronsNeurovascular CouplingSubarachnoid HemorrhageTime FactorsVasoconstrictionCalciumCarbon DioxideCO2in vivoneurovascular couplingparenchymal vesselsSubarachnoid hemorrhage

Identifiers

PMID26676226
PMCPMC5363735
OpenAlexW2205012254

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.