ArticleJournal of ultrasonography2015
Perihepatic lymphadenopathy in children with chronic viral hepatitis.
Article in Journal of ultrasonography, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed, 10 citations in OpenAlex.
- The Enlargement of Abdominal Lymph Nodes Is a Characteristic of Autoimmune Liver Disease.Mediators of inflammation · 2020Article
- Dual energy computed tomography for detection of metastatic lymph nodes in patients with hepatocellular carcinoma.World journal of gastroenterology · 2019Article
- Review of Dancing Parasites in Lymphatic Filariasis.Ultrasound international open · 2019Review
- Ultrasound findings in autoimmune hepatitis.World journal of gastroenterology · 2018Review
- Perihepatic lymphadenopathy in children with chronic viral hepatitis.Journal of ultrasonography · 2015Article
- Role of contrast-enhanced endoscopic ultrasound in lymph nodes.Endoscopic ultrasoundReview
- EUS in pediatric patients.Endoscopic ultrasoundReview
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo assess whether lymph node enlargement in the hepatoduodenal ligament occurs in children with chronic viral hepatitis B and C in comparison to healthy controls. SUBJECT AND
methodsIn 49 patients with chronic viral hepatitis (38 with chronic hepatitis B, 11 with chronic hepatitis C, 31 male, 18 female; age range 1 to 17 years), and in 51 healthy controls (25 male, 26 female; age range 4 to 16 years), the total perihepatic lymph node volume was assessed using transabdominal ultrasonography as previously described in adult patients.
resultsAdequate visualization of the liver hilum was achieved in 46/49 (94%) pediatric patients with chronic viral hepatitis and in 46/51 (90%) pediatric healthy controls. In patients with adequate liver hilum visualization, enlarged perihepatic lymph nodes (longitudinal diameter >14 mm) were detected in 32/46 (70%) patients with chronic viral hepatitis and in 5/46 (11%) healthy controls. The total perihepatic lymph nodes volume [mean ± SD] was 1.0 ± 1.2 mL (0.1-5.4 mL) in patients with chronic viral hepatitis and 0.1 ± 0.1 mL (0.0-0.4 mL) in healthy controls (p < 0.05). A maximal lymph node diameter >14 mm identified patients with chronic viral hepatitis with 70% sensitivity and 89% specificity.
conclusionTransabdominal ultrasound can detect lymph nodes within the hepatoduodenal ligament not only in adults but also in children. Paediatric patients with chronic viral hepatitis have significantly enlarged perihepatic lymph nodes compared to controls. Therefore, sonographic assessment of perihepatic lymphadenopathy might be a non-invasive diagnostic tool to screen paediatric patients for chronic viral hepatitis.
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Registered trials
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